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1,2-Epoxybutane

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Name

1,2-Epoxybutane

EINECS 203-438-2
CAS No. 106-88-7 Density 0.88 g/cm3
Solubility Melting Point
Formula C4H8O Boiling Point 63.4 °C at 760 mmHg
Molecular Weight 72.12 Flash Point -15 °C
Transport Information UN 3022 3/PG 2 Appearance colourless liquid with an unpleasant smell
Safety 9-16-29-36/37-61-19 Risk Codes 11-20/21/22-36/37/38-40-52/53
Molecular Structure Molecular Structure of 106-88-7 (1,2-Epoxybutane) Hazard Symbols FlammableF, HarmfulXn
Synonyms

Butane,1,2-epoxy- (8CI);Oxirane, ethyl- (9CI);1,2-Butene oxide;1,2-Butyleneepoxide;1,2-Butylene oxide;1,2-Epoxybutane;1-Butene oxide;1-Butylene oxide;2-Ethyloxirane;Butene 1,2-epoxide;DL-1,2-Epoxybutane;Ethylethylene oxide;Ethyloxirane;NSC 24240;a-Butylene oxide;

 

1,2-Epoxybutane Toxicity Data With Reference

1.   

skn-rbt 500 mg/24H MLD

   85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,770.
2.   

eye-rbt 100 mg/24H MOD

   85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,770.
3.   

mmo-klp mmol/L

   MUREAV    Mutation Research. 89 (1981),269.
4.   

trn-dmg-orl 5 pph

   ENMUDM    Environmental Mutagenesis. 7 (1985),349.
5.   

mma-ssp 1600 μmol/L

   TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 3 (1983),75.
6.   

orl-rat LD50:500 mg/kg

   NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB81-168510 .
7.   

ihl-rat LCLo:4000 ppm/4H

   AIHAAP    American Industrial Hygiene Association Journal. 23 (1962),95.
8.   

skn-rbt LD50:2100 mg/kg

   AIHAAP    American Industrial Hygiene Association Journal. 23 (1962),95.

1,2-Epoxybutane Consensus Reports

NTP Carcinogenesis Studies (inhalation); Clear Evidence: rat; No Evidence: mouse NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-329 (1988). . Community Right-To-Know List. EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

1,2-Epoxybutane Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion and skin contact. Mildly toxic by inhalation. Experimental reproductive effects. Mutation data reported. Dangerous fire hazard when exposed to heat, flame, or powerful oxidizers. To fight fire, use dry chemical, water spray, mist or fog, alcohol foam. When heated to decomposition it emits acrid smoke and fumes.

1,2-Epoxybutane Standards and Recommendations

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

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