Naproxen sodium

Product Name: Naproxen sodium (CAS NO.26159-34-2)

Molecular Formula: C₁₄H₁₃NaO₃
Molecular Weight: 252.25g/mol
Mol File: 26159-34-2.mol
EINECS: 247-486-2
Appearance: White Powder
Melting Point: 250-251°C
Boiling point: 403.9 °C at 760 mmHg
Flash Point: 154.5 °C
Enthalpy of Vaporization: 69.1 kJ/mol
Vapour Pressure: 3.01E-07 mmHg at 25°C
H-Bond Donor: 0
H-Bond Acceptor: 3
Structure Descriptors of Naproxen sodium (CAS NO.26159-34-2):
  IUPAC Name: sodium 2-(6-methoxynaphthalen-2-yl)propanoate
  Canonical SMILES: CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]
  InChI: InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1 
  InChIKey: CDBRNDSHEYLDJV-UHFFFAOYSA-M
Product Categories: Active Pharmaceutical Ingredients; Intermediates & Fine Chemicals; Pharmaceuticals; API's

 Naproxen sodium (CAS NO.26159-34-2) is a non-steroidal anti-inflammatory drug commonly used for  fever, inflammation the reduction of moderate to severe pain,and stiffness caused by conditions such as psoriatic arthritis, gout, ankylosing spondylitis,osteoarthritis, rheumatoid arthritis,  and the treatment of primary dysmenorrhea.  

In August 2006, the Journal Birth Defects Research Part B published results indicating that pregnant women who take NSAIDs including naproxen in the first trimester run an increased risk of having a child with congenital birth defects, particularly heart anomalies
IP110 Naproxen Tablets: Like other NSAIDs, naproxen can inhibit the excretion of sodium and LITHIUM. Extreme care must be taken by those who use this drug along with LITHIUM supplements. Naproxen is also not recommended for use with NSAIDs of the salicylate family or with anticoagulants  Naproxen preparations containing sodium are not recommended for use in patients with sodium-sensitive hypertension, due to potential adverse effects on blood pressure in this small subset of hypertensive.
Safety Information of Naproxen sodium (CAS NO.26159-34-2):
Hazard Codes: Xn
Risk Statements: 22  
R22:Harmful if swallowed.
RIDADR: 3249
RTECS: QJ1047000
HazardClass: 6.1(b)
PackingGroup: III

 Naproxen sodium , its CAS NO. is 26159-34-2, the synonyms are (-)-Sodium (S)-6-methoxy-alpha-methyl-2-naphthaleneacetate ; 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, sodium salt, (S)- ; 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, sodium salt, L-(-)- ; Sodium (-)-2-(6-methoxy-2-naphthyl)propionate .