Reference

Prevention of induction of suppressor activity in human mononuclear leukocytes by ascorbate and cysteine in vitro

Prevention of induction of suppressor activity in human mononuclear leukocytes by ascorbate and cysteine in vitro. Eftychis, H.; Anderson, R. (Inst. Pathol., Univ. Pretoria, Pretoria, S. Afr.). Int. J. Vitam. Nutr. Res., 53(4), 398-401 (English) 1983. CODEN: IJVNAP. ISSN: 0300-9831. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Concanavalin A (con A) [11028-71-0] and the nonsteroidal anti-inflammatory drug benoxaprofen [51234-28-7] caused increased oxidative metab. and suppressor activity in human mononuclear leukocytes (MNL) in vitro. The relation between enhanced oxidative metab. and suppressor activity in MNL was investigated using the water-sol. antioxidants ascorbate [50-81-7] and cysteine [52-90-4] at fixed concns. of 1 ′ 10-3M. Ascorbate and cysteine inhibited both the induction of suppressor activity and increased oxidative metab. in MNL caused by con A and benoxaprofen.Except for chemicals metioned above, 51234-28-7 and 11028-71-0 are also used. It is proposed that ascorbate and cysteine prevent the induction of nonspecific suppressor activity in MNL by an antioxidant mechanism. .

Effect of histidine, cysteine, glutathione or beef on iron absorption in humans

Effect of histidine, cysteine, glutathione or beef on iron absorption in humans. Layrisse, Miguel; Martinez-Torres, Carlos; Leets, Irene; Taylor, Peter; Ramirez, Jose (Lab. Fisiopatol., Inst. Venez. Invest. Cient., Caracas, Venez.). J. Nutr., 114(1), 217-23 (English) 1984. CODEN: JONUAI. 71-00-1 and 52-90-4 are cas registry numbers of chemicals which are used as reagents here. ISSN: 0022-3166. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) One hundred thirteen subjects participated in Fe absorption studies in which histidine [71-00-1], cysteine [52-90-4], reduced glutathione [70-18-8], or beef were administered with test meals. Increasing doses of histidine from 416 to 2080 mg did not affect the absorption of 2 mg of corn Fe. Reduced glutathione significantly increased the absorption from nonheme and heme Fe present in black beans, corn, and Hb. Increasing doses of either cysteine or glutathione produce the same trend in the increase of absorption from corn Fe as that obsd. from beef. The results suggest that the effect of cysteine on Fe absorption is similar in the peptide form and as a single mol. .