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5-BROMOSALICYLIC ACID

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Name

5-BROMOSALICYLIC ACID

EINECS 201-917-0
CAS No. 89-55-4 Density 1.861 g/cm3
PSA 57.53000 LogP 1.85290
Solubility Soluble in water Melting Point 162-166 °C
Formula C7H5BrO3 Boiling Point 338.1 °C at 760 mmHg
Molecular Weight 217.019 Flash Point 158.3 °C
Transport Information N/A Appearance white to slightly beige powder
Safety 37/39-26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 89-55-4 (5-Bromosalicylic acid) Hazard Symbols IrritantXi
Synonyms

Salicylicacid, 5-bromo- (6CI,8CI);2-Hydroxy-5-bromobenzoic acid;5-Bromo-2-hydroxybenzoic acid;NSC 3981;NSC 52393;

Article Data 72

5-BROMOSALICYLIC ACID Synthetic route

69-72-7

salicylic acid

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With tetrapropylammonium nonabromide In dichloromethane at 23℃; for 0.5h; Inert atmosphere;95%
With sodium vanadate; aluminum tri-bromide; tetrabutylammomium bromide; oxygen In 1,4-dioxane; water at 80℃; for 8h; Reagent/catalyst; Solvent; Temperature;93.1%
With 1-butyl-3-methylpyridinium tribromide at 20℃; for 1h;89%
1761-61-1

5-bromosalicyclaldehyde

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With sodium chlorite; sodium methylate In dimethyl sulfoxide84%
21740-00-1

5-bromo-2-iodo-benzoic acid

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With copper(I) oxide; 1-D-O-Methyl-chiro-inositol; sodium hydroxide In water at 100℃; for 6h;77%
82486-43-9

2-hydroxy-5-bromobenzaldehyde oxime

A

89-55-4

5-bromosalicyclic acid

B

1761-61-1

5-bromosalicyclaldehyde

Conditions
ConditionsYield
With calcium hypochlorite; montmorillonite K-10 In chloroform at 20℃; for 4h;A 2.5%
B 69%

4-bromo-2-propionylphenylmethylphenylcarbamate

A

5827-78-1

N-methyl-N-phenylpropanamide

B

89-55-4

5-bromosalicyclic acid

C

17764-93-1

5-bromo-2-hydroxypropiophenone

Conditions
ConditionsYield
With water; sodium hydride In tetrahydrofuran for 24h; Reflux;A 60%
B 43%
C n/a
56-23-5

tetrachloromethane

106-41-2

4-bromo-phenol

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With sodium hydroxide
109-72-8, 29786-93-4

n-butyllithium

60-29-7

diethyl ether

615-58-7

2,4-dibromophenol

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
anschliessend Behandeln mit festem Kohlendioxid;
615-58-7

2,4-dibromophenol

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With n-butyllithium; diethyl ether anschliessendes Behandeln mit CO2;
10268-63-0

phenyl 5-bromo-2-hydroxybenzoate

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
bei der Verseifung;
4068-76-2

5-bromo-2-hydroxy-benzoic acid methyl ester

89-55-4

5-bromosalicyclic acid

Conditions
ConditionsYield
With sodium hydroxide

5-BROMOSALICYLIC ACID Chemical Properties

5-Bromosalicylic acid(89-55-4) is the chemical compound with the formula C7H5BrO3.Its molar weight is 217.02g/mol.
5-Bromosalicylic acid(89-55-4) is also named 2-Hydroxy-5-bromobenzoic acid;3-bromo-6-hydroxy-benzoicaci;5-bromo-2-hydroxy-benzoicaci;5-bromo-salicylicaci;Benzoic acid, 3-bromo-6-hydroxy-;Benzoic acid, 5-bromo-2-hydroxy-;Benzoicacid,5-bromo-2-hydroxy-;Salicylic acid, 5-bromo-.
Melting Point: 162-166 oC
Boiling Point: 338.1 oC at 760 mmHg
Flash Point: 158.3 oC
Water Solubility: Soluble
Index of Refraction: 1.654 
Molar Refractivity: 42.75 cm3 
Molar Volume: 116.5 cm3  
Surface Tension: 68.1 dyne/cm 
Density: 1.861 g/cm3 
Enthalpy of Vaporization: 61.36 kJ/mol 
Vapour Pressure: 3.93E-05 mmHg at 25 oC
The chemical structure of 5-Bromosalicylic acid(89-55-4) is
.

5-BROMOSALICYLIC ACID Uses

5-Bromosalicylic acid(89-55-4) is used as organic synthesis.

5-BROMOSALICYLIC ACID Toxicity Data With Reference

1.   

ivn-mus LD50:100 mg/kg

   CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#04478 .

5-BROMOSALICYLIC ACID Consensus Reports

Reported in EPA TSCA Inventory.

5-BROMOSALICYLIC ACID Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of Br.
Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38:  Irritating to eyes, respiratory system and skin  
Safety Statements: 37/39-26-36
37/39: Wear suitable gloves and eye/face protection 
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36: Wear suitable protective clothing 
RTECS: VO1850000.

5-BROMOSALICYLIC ACID Specification

5-Bromosalicylic acid(89-55-4)The extinguishing agents of 5-Bromosalicylic acid(89-55-4) is dry powder, carbon dioxide, water mist.
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