13472-83-8Relevant articles and documents
Cu(I)/sucrose-catalyzed hydroxylation of arenes in water: The dual role of sucrose
Murata, Shigeo,Takagi, Mio,Takita, Ryo,Watanabe, Ayako,Watanabe, Kohei
supporting information, p. 7827 - 7831 (2020/11/02)
A protocol for the hydroxylation of aryl halides catalyzed by copper(I) and sucrose in neat water has been developed. The dual role of sucrose, the reaction pathway, and the high selectivity for hydroxylation were investigated using a combination of experimental and theoretical techniques. This journal is
METHOD FOR PRODUCING OXYPYRIDINE COMPOUND AND ATPENIN ANALOG
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Paragraph 0108; 0116-0118, (2019/08/06)
PROBLEM TO BE SOLVED: To provide a method for producing an oxypyridine compound at low cost and/or with high efficiency. SOLUTION: A method for producing a compound represented by formula (I) [R1, R2, R3 and R4
Total synthesis of 4-epi-atpenin A5 as a potent nematode complex II inhibitor
Lee, Daiki,Kondo, Hiroki,Kuwayama, Yui,Takahashi, Kento,Arima, Shiho,Omura, Satoshi,Ohtawa, Masaki,Nagamitsu, Tohru
, p. 3178 - 3185 (2019/04/10)
It is clear that atpenins and their analogs are useful chemical tools for elucidation of complex II functionality and that they could act as lead compounds for the development of novel helminth complex II-specific inhibitors. Recently, we discovered 4-epi
Chemoselective oxidation of aryl organoboron systems enabled by boronic acid-selective phase transfer
Molloy, John J.,Clohessy, Thomas A.,Irving, Craig,Anderson, Niall A.,Lloyd-Jones, Guy C.,Watson, Allan J. B.
, p. 1551 - 1559 (2017/02/10)
We report the direct chemoselective Brown-type oxidation of aryl organoboron systems containing two oxidizable boron groups. Basic biphasic reaction conditions enable selective formation and phase transfer of a boronic acid trihydroxyboronate in the presence of boronic acid pinacol (BPin) esters, while avoiding speciation equilibria. Spectroscopic investigations validate a base-promoted phase-selective discrimination of organoboron species. This phenomenon is general across a broad range of organoboron compounds and can also be used to invert conventional protecting group strategies, enabling chemoselective oxidation of BMIDA species over normally more reactive BPin substrates. We also demonstrate the selective oxidation of diboronic acid systems with chemoselectivity predictable a priori. The utility of this method is exemplified through the development of a chemoselective oxidative nucleophile coupling.