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2-Methoxypyridin-3-ol, a pyridine derivative with the molecular formula C6H7NO2, is a chemical compound featuring a methoxy group and a hydroxyl group attached to the third carbon atom. It is widely recognized for its versatility in both industrial and scientific applications, particularly in the synthesis of pharmaceuticals and fine chemicals, as well as its role as a reagent in organic chemistry and a flavoring agent in the food industry.

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  • 13472-83-8 Structure
  • Basic information

    1. Product Name: 2-Methoxypyridin-3-ol
    2. Synonyms: 2-Methoxypyridin-3-ol;2-Methoxy-3-hydroxypyridine;2-Methoxy-3-pyridinol
    3. CAS NO:13472-83-8
    4. Molecular Formula: C6H7NO2
    5. Molecular Weight: 125.12528
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 13472-83-8.mol
  • Chemical Properties

    1. Melting Point: 68-69℃
    2. Boiling Point: 82℃
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.190±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. PKA: 8.94±0.10(Predicted)
    10. CAS DataBase Reference: 2-Methoxypyridin-3-ol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Methoxypyridin-3-ol(13472-83-8)
    12. EPA Substance Registry System: 2-Methoxypyridin-3-ol(13472-83-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 13472-83-8(Hazardous Substances Data)

13472-83-8 Usage

Uses

Used in Pharmaceutical and Fine Chemicals Synthesis:
2-Methoxypyridin-3-ol is utilized as a building block for the creation of various pharmaceuticals and fine chemicals. Its unique structure allows for the development of compounds with specific therapeutic properties, making it a valuable component in the medicinal chemistry field.
Used in Organic Chemistry Reactions:
As a reagent, 2-Methoxypyridin-3-ol is employed in the formation of heterocyclic compounds, which are essential in the synthesis of complex organic molecules. Its presence in these reactions contributes to the diversity of chemical products available for research and commercial purposes.
Used in the Food Industry:
2-Methoxypyridin-3-ol is used as a flavoring agent, adding unique taste profiles to food products. Its application in this industry highlights its potential to enhance the sensory experience of consumers while maintaining the quality and safety of food items.
Used in Biological Research:
2-Methoxypyridin-3-ol has been studied for its potential biological activities, indicating its use in scientific research to explore its effects on biological systems. This research could lead to new discoveries in medicine and biology, further expanding the compound's applications.

Check Digit Verification of cas no

The CAS Registry Mumber 13472-83-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,7 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13472-83:
(7*1)+(6*3)+(5*4)+(4*7)+(3*2)+(2*8)+(1*3)=98
98 % 10 = 8
So 13472-83-8 is a valid CAS Registry Number.

13472-83-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxy-3-pyridinol

1.2 Other means of identification

Product number -
Other names Glycerinaldehyd-2-methylaether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13472-83-8 SDS

13472-83-8Relevant articles and documents

Cu(I)/sucrose-catalyzed hydroxylation of arenes in water: The dual role of sucrose

Murata, Shigeo,Takagi, Mio,Takita, Ryo,Watanabe, Ayako,Watanabe, Kohei

supporting information, p. 7827 - 7831 (2020/11/02)

A protocol for the hydroxylation of aryl halides catalyzed by copper(I) and sucrose in neat water has been developed. The dual role of sucrose, the reaction pathway, and the high selectivity for hydroxylation were investigated using a combination of experimental and theoretical techniques. This journal is

METHOD FOR PRODUCING OXYPYRIDINE COMPOUND AND ATPENIN ANALOG

-

Paragraph 0108; 0116-0118, (2019/08/06)

PROBLEM TO BE SOLVED: To provide a method for producing an oxypyridine compound at low cost and/or with high efficiency. SOLUTION: A method for producing a compound represented by formula (I) [R1, R2, R3 and R4

Total synthesis of 4-epi-atpenin A5 as a potent nematode complex II inhibitor

Lee, Daiki,Kondo, Hiroki,Kuwayama, Yui,Takahashi, Kento,Arima, Shiho,Omura, Satoshi,Ohtawa, Masaki,Nagamitsu, Tohru

, p. 3178 - 3185 (2019/04/10)

It is clear that atpenins and their analogs are useful chemical tools for elucidation of complex II functionality and that they could act as lead compounds for the development of novel helminth complex II-specific inhibitors. Recently, we discovered 4-epi

Chemoselective oxidation of aryl organoboron systems enabled by boronic acid-selective phase transfer

Molloy, John J.,Clohessy, Thomas A.,Irving, Craig,Anderson, Niall A.,Lloyd-Jones, Guy C.,Watson, Allan J. B.

, p. 1551 - 1559 (2017/02/10)

We report the direct chemoselective Brown-type oxidation of aryl organoboron systems containing two oxidizable boron groups. Basic biphasic reaction conditions enable selective formation and phase transfer of a boronic acid trihydroxyboronate in the presence of boronic acid pinacol (BPin) esters, while avoiding speciation equilibria. Spectroscopic investigations validate a base-promoted phase-selective discrimination of organoboron species. This phenomenon is general across a broad range of organoboron compounds and can also be used to invert conventional protecting group strategies, enabling chemoselective oxidation of BMIDA species over normally more reactive BPin substrates. We also demonstrate the selective oxidation of diboronic acid systems with chemoselectivity predictable a priori. The utility of this method is exemplified through the development of a chemoselective oxidative nucleophile coupling.

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