13494-10-5

Basic information

• Product Name: 2',3'-DIHYDROXYACETOPHENONE
• Synonyms: 2',3'-DIHYDROXYACETOPHENONE;3-Acetylcatechol;1-(2,3-dihydroxyphenyl)ethan-1-one;3-Acetyl-1,2-benzenediol;Ethanone,1-(2,3-dihydroxyphenyl)-
• CAS NO: 13494-10-5
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 152.15
• Product Categories: Aromatics;Intermediates
• Mol File: 13494-10-5.mol

Chemical Properties

• Melting Point: 198-200℃
• Boiling Point: 294 °C at 760 mmHg
• Flash Point: 145.9 °C
• Appearance: /
• Density: 1.291g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Methanol
• PKA: 8.98±0.10(Predicted)
• CAS DataBase Reference: 2',3'-DIHYDROXYACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3'-DIHYDROXYACETOPHENONE(13494-10-5)
• EPA Substance Registry System: 2',3'-DIHYDROXYACETOPHENONE(13494-10-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 13494-10-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2',3'-DIHYDROXYACETOPHENONE is used as a reagent for the synthesis of antiproliferative agents, which are compounds that inhibit cell proliferation and are often used in cancer treatment. Its role in the synthesis of these agents is due to its ability to be chemically modified and incorporated into the structure of the final product.
2',3'-DIHYDROXYACETOPHENONE is also used as a reagent for the synthesis of opioid receptor agonists, which are drugs that bind to and activate opioid receptors in the nervous system. These agonists are used to treat pain and are also involved in the management of addiction and other neurological disorders.
Furthermore, 2',3'-DIHYDROXYACETOPHENONE is used in the synthesis of anticoagulants, which are medications that help prevent blood clots from forming. These compounds are essential in the treatment and prevention of conditions such as deep vein thrombosis, pulmonary embolism, and stroke.

Preparation

Also obtained by bioconversion of acetophenone through the living cells of Escherichia coli carrying plasmid pUC6256B expressing todCI-bphA2A3A4 and bphB (39.2%).

Upstream product

• 703-98-0 1-(2-hydroxy-3-methoxyphenyl)ethanone 
• 120-80-9 benzene-1,2-diol 
• 64-19-7 acetic acid 
• 635-67-6 dimethyl phthalate 
• 75-36-5 acetyl chloride 
• 5653-62-3 2,3-dimethoxybenzonitrile 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 6848-73-3 1-(2,3-dimethoxyphenyl)-1-ethanol 
• 2848-25-1 2-acetoxyphenol 
• 38480-94-3 2,3-dimethoxyacetophenone 

Downstream Products

• 743466-69-5 8-hydroxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one 
• 859441-87-5 2-(3,4-dimethoxy-phenyl)-8-hydroxy-3-veratroyl-chromen-4-one 
• 710337-68-1 3-benzoyl-8-hydroxy-2-phenyl-chromen-4-one 
• 743438-43-9 8-hydroxy-2-(4-methoxy-phenyl)-chromen-4-one 
• 88086-96-8 2,3-Dihydroxyacetophenone 3-O-(2,3,4,6-Tetra-O-acetyl-β-D-galactopyranoside) 
• 69079-92-1 1-[2-Hydroxy-3-(3-phenoxy-propoxy)-phenyl]-ethanone 
• 108718-31-6 4-Chlor-2',3'-dihydroxy-chalkon 
• 22129-67-5 2,3-Dihydroxy-chalkon 
• 880547-13-7 1-(2-hydroxy-3-(methoxymethoxy)phenyl)ethan-1-one 
• 863191-11-1 2,3-dimethoxymethoxyacetophenone 
• 92496-66-7 8-hydroxyflavanone 
• 22129-67-5 2',3'-dihydroxychalcone 
• 88087-06-3 3,2',3'-Trihydroxy-4-methoxychalcone 3'-O-β-D-galactopyranoside 
• 77298-64-7 8-hydroxyflavone 

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