13505-41-4

Basic information

• Product Name: 4,4,4-TRICHLORO-3-HYDROXY-1-PHENYL-BUTAN-1-ONE
• Synonyms: Butyrophenone,4,4,4-trichloro-3-hydroxy- (8CI);NSC 173296
• CAS NO: 13505-41-4
• Molecular Formula: C₁₀H₉Cl₃O₂
• Molecular Weight: 267.5363
• Mol File: 13505-41-4.mol

Chemical Properties

• Boiling Point: 396.2 °C at 760 mmHg
• Flash Point: 193.4 °C
• Appearance: /
• Density: 1.437 g/cm³
• Vapor Pressure: 5.46E-07mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 4,4,4-TRICHLORO-3-HYDROXY-1-PHENYL-BUTAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-TRICHLORO-3-HYDROXY-1-PHENYL-BUTAN-1-ONE(13505-41-4)
• EPA Substance Registry System: 4,4,4-TRICHLORO-3-HYDROXY-1-PHENYL-BUTAN-1-ONE(13505-41-4)

Safety Data

• Hazardous Substances Data: 13505-41-4(Hazardous Substances Data)

Usage

Uses

Used in Personal Care Products:
Triclosan is used as an antimicrobial agent in personal care products such as soaps, toothpaste, and deodorants. Its application in these products is aimed at reducing or preventing the growth of bacteria, fungi, and other microorganisms, thereby promoting better hygiene and reducing the risk of infections.
Used in Industrial Settings:
In the industrial sector, Triclosan is utilized as a preservative in textiles and plastic products. Its inclusion in these materials helps to prevent the growth of microorganisms, thereby extending the lifespan of the products and reducing the risk of microbial contamination.
Used in Antimicrobial Coatings:
Triclosan is also used in the development of antimicrobial coatings for various surfaces, including medical devices, hospital equipment, and household items. These coatings are designed to inhibit the growth of bacteria and other microorganisms, reducing the risk of infections and promoting a cleaner and safer environment.
However, it is important to note that due to the potential negative effects of Triclosan on human health and the environment, some regulatory agencies have banned or restricted its use in certain products. As a result, there is a growing interest in finding alternative antimicrobial agents that are both effective and environmentally friendly.

InChI:InChI=1/C10H9Cl3O2/c11-10(12,13)9(15)6-8(14)7-4-2-1-3-5-7/h1-5,9,15H,6H2

Upstream product

• 75-87-6 chloral 
• 98-86-2 acetophenone 
• 302-17-0 chloral hydrate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 13735-81-4 1-styrenyloxytrimethylsilane 

Downstream Products

• 99360-92-6 Phenyl-2,3,3,3-tetrachlor-propylketon 
• 21100-66-3 4,4,4-trichloro-1-phenyl-but-2-en-1-one 
• 69809-06-9 4,4,4-trichloro-3-hydroxy-1-phenyl-butan-1-one oxime 
• 69809-02-5 4,4,4-trichloro-3-hydroxy-1-phenyl-butan-1-one-phenylhydrazone 
• 65245-10-5 2-hydroxy-4-oxo-4-phenylbutanoic acid 
• 64-18-6 formic acid 
• 77953-17-4 4-oxo-2-phenacyl-4-phenyl-butyric acid 
• 65-85-0 benzoic acid 
• 53779-78-5 (E)-1-phenyl-4,4,4-trichloro-2-penten-1-one 
• 807331-42-6 4,4-dichloro-1-phenylbut-3-en-1-one 
• 24886-77-9 1.3.3-Trichlor-2-propenyl-phenyl-keton 

Relevant articles and documents

First synthesis of 1-aryl-4,4-dichlorobut-3-en-1-ones. The electrochemical reduction of 1-aryl-4,4,4-trichlorobut-2-en-1-ones as a key step

The first method for the synthesis of 1-aryl-4,4-dichlorobut-3-en-1-ones is reported. Treatment of acetophenones with anhydrous chloral leads to 1-aryl-4,4,4-trichloro-3-hydroxybutan-1-ones in near quantitative yields. These compounds were efficiently deh

First synthesis of 3-aryl-5-dichloromethyl-2-pyrazolines. The electrochemical generation of 2,2-dichlorovinylacetophenones as a key step

An efficient synthetic route to the title compounds has been established. Chloralacetophenones 2 were prepared by treatment of acetophenones 1 with anhydrous chloral. Dehydration of intermediates 2 under acidic conditions yielded 2,2,2-trichloroethylidene