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ANILINO(PHENYL)ACETIC ACID, also known as N-phenyl anthranilic acid, is a chemical compound belonging to the class of aromatic carboxylic acids. It is characterized by its white to off-white crystalline powder form, a distinctive odor, and sparing solubility in water. ANILINO(PHENYL)ACETIC ACID is recognized for its analgesic, anti-inflammatory, and antipyretic properties, positioning it as a promising intermediate in the pharmaceutical industry for the synthesis of various medicinal compounds. Its potential in treating chronic pain and inflammatory conditions further underscores its significance in drug development.

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  • 3684-12-6 Structure
  • Basic information

    1. Product Name: ANILINO(PHENYL)ACETIC ACID
    2. Synonyms: PHENYL-PHENYLAMINO-ACETIC ACID;alpha-(phenylamino)-benzeneaceticaci;n,2-diphenyl-glycin;n,2-diphenylglycine;CHEMBRDG-BB 4140263;ANILINO(PHENYL)ACETIC ACID;2-Anilino-2-phenylacetic acid;anilino(phenyl)acetic acid(SALTDATA: FREE)
    3. CAS NO:3684-12-6
    4. Molecular Formula: C14H13NO2
    5. Molecular Weight: 227.26
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 3684-12-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 412.3 °C at 760 mmHg
    3. Flash Point: 203.2 °C
    4. Appearance: /
    5. Density: 1.252 g/cm3
    6. Vapor Pressure: 1.54E-07mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: ANILINO(PHENYL)ACETIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: ANILINO(PHENYL)ACETIC ACID(3684-12-6)
    12. EPA Substance Registry System: ANILINO(PHENYL)ACETIC ACID(3684-12-6)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 3684-12-6(Hazardous Substances Data)

3684-12-6 Usage

Uses

Used in Pharmaceutical Industry:
ANILINO(PHENYL)ACETIC ACID is used as a key intermediate in the synthesis of pharmaceutical compounds due to its versatile chemical properties and potential therapeutic effects.
Used in Pain Management:
ANILINO(PHENYL)ACETIC ACID is used as an analgesic agent for its pain-relieving properties, offering a potential solution for managing various types of pain.
Used in Anti-Inflammatory Treatments:
Leveraging its anti-inflammatory characteristics, ANILINO(PHENYL)ACETIC ACID is utilized in the development of treatments aimed at reducing inflammation and associated discomfort.
Used in Antipyretic Formulations:
Capitalizing on its antipyretic properties, ANILINO(PHENYL)ACETIC ACID is employed in the creation of medications designed to reduce fever.
Used in Chronic Pain and Inflammatory Condition Treatments:
ANILINO(PHENYL)ACETIC ACID is explored for its potential application in treating chronic pain and inflammatory conditions, offering hope for more effective therapeutic interventions in these areas.
Proper handling and storage are crucial for the safe use of ANILINO(PHENYL)ACETIC ACID in both laboratory and industrial settings, ensuring that its benefits can be harnessed while minimizing any risks associated with its chemical nature.

Check Digit Verification of cas no

The CAS Registry Mumber 3684-12-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3684-12:
(6*3)+(5*6)+(4*8)+(3*4)+(2*1)+(1*2)=96
96 % 10 = 6
So 3684-12-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H13NO2/c16-14(17)13(11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h1-10,13,15H,(H,16,17)/p-1/t13-/m1/s1

3684-12-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-anilino-2-phenylacetic acid

1.2 Other means of identification

Product number -
Other names N,2-Diphenylglycine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3684-12-6 SDS

3684-12-6Relevant articles and documents

Integrated Flow Synthesis of α-Amino Acids byIn SituGeneration of Aldimines and Subsequent Electrochemical Carboxylation

Naito, Yuki,Nakamura, Yuto,Shida, Naoki,Senboku, Hisanori,Tanaka, Kenta,Atobe, Mahito

, p. 15953 - 15960 (2021/07/20)

The synthesis of α-amino acids was carried out in a continuous flow system. In this system, aldimines were efficiently generatedin situvia the dehydration-condensation of aldehydes with anilines in a desiccant bed column filled with 4 ? molecular sieves d

FULLERENE DERIVATIVE AND n-TYPE SEMICONDUCTOR MATERIAL

-

Paragraph 0249; 0250; 0251; 0252; 0253; 0254; 0255, (2018/10/21)

An object of the present invention is to provide a novel fullerene derivative usable in n-type semiconductor materials for organic thin-film solar cells and the like. The object is achieved by a fullerene derivative represented by formula (1) wherein Rs

A synthesis of α-amino acids via direct reductive carboxylation of imines with carbon dioxide

Sathe, Ajay A.,Hartline, Douglas R.,Radosevich, Alexander T.

supporting information, p. 5040 - 5042 (2013/06/05)

A method for the synthesis of α-amino acids by direct reductive carboxylation of aromatic imines with CO2 is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis. The Royal Society of Chemistry 2013.

Nanoparticle catalyzed reaction (NPCR): ZnO-NP catalyzed Ugi-reaction in aqueous medium

Kumar, Atul,Saxena, Deepti,Gupta, Maneesh Kumar

supporting information, p. 2699 - 2703 (2013/10/08)

The first ZnO-NP catalyzed Ugi type three-component (AB2C) reaction has been developed for the synthesis of 2-arylamino-2- phenylacetimidamide from an aldehyde, amine and isocyanide in aqueous media. This nanoparticle catalysed reaction (NPCR)

Boric acid catalyzed Ugi three-component reaction in aqueous media

Kumar, Atul,Saxena, Deepti,Gupta, Maneesh Kumar

, p. 4610 - 4612 (2013/04/24)

B(OH)3 catalyzed Ugi three-component reaction for the synthesis of 2-arylamino-2-phenylacetamide has been developed using aldehydes, amines, and isocyanides in water. The synthesized 2-arylamino-2-phenylacetamides were efficiently converted int

ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF

-

, (2012/01/12)

The present invention relates to alkaloid aminoester compounds which act as muscarinic receptor antagonists, processes for their preparation, compositions comprising them, and therapeutic uses thereof.

ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF

-

, (2012/01/12)

The present invention relates to alkaloid aminoester compounds which act as muscarinic receptor antagonists, processes for the preparation of such a compound, compositions which contain such a compound, and therapeutic uses of such a compound.

ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF

-

Page/Page column 32, (2012/01/13)

The present invention relates to alkaloid aminoester derivatives acting as muscarinic receptor antagonists, processes for their preparation, compositions comprising them and therapeutic uses thereof.

ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF

-

Page/Page column 26, (2012/01/13)

The present invention relates to alkaloid aminoester derivatives acting as muscarinic receptor antagonists, processes for their preparation, compositions comprising them and therapeutic uses thereof.

Palladium-catalyzed coupling reaction of amino acids (esters) with aryl bromides and chlorides

Ma, Fangfang,Xie, Xiaomin,Ding, Lina,Gao, Jinsheng,Zhang, Zhaoguo

experimental part, p. 9405 - 9410 (2011/12/14)

The bulky and electron-rich MOP type ligands and Pd(dba)2 combinations showed high efficiency for the coupling reactions of amino acids and inactive aryl halides to give N-aryl amino acids. Under the catalytic conditions, not only α-amino acids, but also β-, γ-, and δ-amino acids have been coupled with aryl chlorides in moderate to high yields; in the case of optically pure β-amino acids as substrates, the optical purities of the coupling products retained.

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