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1-((S)-PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL, with the molecular formula C27H27NO, is a chiral chemical compound featuring a naphthalene ring, a piperidine ring, a hydroxyl group, and a phenyl group. Its 3D structure and pharmacological activity suggest potential applications in the medical field, while its chiral nature is significant for research in stereochemistry and asymmetric synthesis.

500352-92-1

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500352-92-1 Usage

Uses

Used in Pharmaceutical Industry:
1-((S)-PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL is used as a pharmacologically active compound for its potential applications in medicine due to its unique structure and chiral properties.
Used in Research and Development:
1-((S)-PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL is used as a key compound in the study of stereochemistry and asymmetric synthesis, contributing to the advancement of chemical and pharmaceutical research.
Used in Drug Design and Synthesis:
1-((S)-PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL is utilized as a building block or template in the design and synthesis of new drugs, taking advantage of its pharmacological activity and structural features.

Check Digit Verification of cas no

The CAS Registry Mumber 500352-92-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,3,5 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 500352-92:
(8*5)+(7*0)+(6*0)+(5*3)+(4*5)+(3*2)+(2*9)+(1*2)=101
101 % 10 = 1
So 500352-92-1 is a valid CAS Registry Number.

500352-92-1Relevant articles and documents

Facile synthesis of aminoalkyl naphthols and single crystal X-ray, computational studies on 1-[morpholino(thiophen-2-yl)methyl]naphthalen-2-ol

Harichandran, G.,Muthu, S.,Surya, C. P.

, (2021/06/25)

An efficient, eco-friendly protocol is developed for the synthesis of 1- (α-aminoalkyl)-2-naphthol derivatives via one-pot three-component reaction of 2-naphthol, aromatic aldehydes and piperidine or morpholine in the presence of Amberlite IRA-400 Cl resi

An efficient, multicomponent synthesis of aminoalkylnaphthols via Betti reaction using ZSM-5 as a recoverable and reusable catalyst

Keri, Rangappa S.,Patil, Mahadeo,Budagumpi, Srinivasa,Sasidhar, Balappa S.

, (2021/05/27)

The design and application of environmentally friendly catalysts to reduce the number of toxic wastes are critical for improving the chemical synthetic protocols. A simple, mild, efficient, and eco-friendly method was developed for the synthesis of a seri

Synthesis of 1-aminoalkyl-2-naphthols derivatives using an engineered copper-based nanomagnetic catalyst (Fe3O4@CQD@Si (OEt)(CH2)3NH@CC@N3@phenylacetylene@Cu)

Akbarpour, Tahereh,Khazaei, Ardeshir,Sarmasti, Negin,Yousefi Seyf, Jaber

, (2021/07/26)

In the present study, a molecular level engineered-based method was used to synthesis a copper-based nanomagnetic catalyst (Fe3O4@CQD@Si (OEt)(CH2)3NH@CC@N3@phenylacetylene@Cu). The as-synthesized cat

Core–shell structured magnetic mesoporous silica-titania: A novel, powerful and recoverable nanocatalyst

Vahidian, Marziyeh,Elhamifar, Dawood,Shaker, Masoumeh

, (2020/01/08)

In this research, a novel core–shell nanostructured magnetic Ti-silica (Mag?MCM-41/TiO2) is synthesized, characterized and its catalytic application is investigated in the production of 1-(α-aminoalkyl)-2-naphthols. The Mag?MCM-41/TiO2 was prepared via surfactant directed hydrolysis and co-condensation of tetramethoxysilane (TMOS) around Mag?SiO2 NPs followed by treatment with tetrabutylorthotitanate (Ti(OtBu)4). The Mag?MCM-41/TiO2 catalyst was characterized using VSM, FTIR, EDX, SEM, TEM and PXRD. The Mag?MCM-41/TiO2 was applied as an efficient catalyst in the synthesis of 1-(α-aminoalkyl)-2-naphthols under ultrasonic conditions at 50 °C. This nanocatalyst was recovered and reused for several times under applied conditions.

Design and identification of nano-Mg-[4-methoxy phenyl-salicylaldimine–methyl-pyranopyrzole] Cl2 and its catalytic application on the preparation of 1-(α-aminoalkyl)-2-naphthols

Goudarziafshar, Hamid,Moosavi-Zare, Ahmad Reza,Hasani, Jafar

, (2020/01/25)

Nano-Mg- [4-methoxy phenylsalicylaldiminemethylpyranopyrazole]Cl2 (nano-[Mg-4MSMP]Cl2) as a nano-Schiff base complex was prepared and fully characterized using some various techniques including fourier transform infrared spectroscopy

Magnetic nanocrystallites strontium hexaferrite as an efficient catalyst in the green Betti reaction

Mohammadi Ziarani, Ghodsi,Kazemi Asl, Zhila,Gholamzadeh, Parisa,Badiei, Alireza,Afshar, Morteza

, p. 515 - 520 (2019/05/15)

The sol–gel auto-combustion method was applied for preparation of SrFe12O19 magnetic nanoparticles (MNPs). Then, the prepared SrFe12O19 was analyzed by VSM, FT-IR, SEM, N2 adsorption-desorption and XR

Synthesis of Betti base derivatives catalyzed by nano-CuO-ionic liquid and experimental and quantum chemical studies on corrosion inhibition performance of them

Teimuri-Mofrad, Reza,Ahadzadeh, Iraj,Gholamhosseini-Nazari, Mahdi,Esmati, Somayeh,Shahrisa, Aziz

, p. 2913 - 2927 (2018/02/06)

In this research, for the first time, aminonaphthol derivatives were introduced as efficient corrosion inhibitors. A linear polarization method was employed to investigate the corrosion inhibitory effect of the synthesized aminonaphthols at a concentratio

Microwave-assisted nanocatalysis: A CuO NPs/rGO composite as an efficient and recyclable catalyst for the Petasis-borono-Mannich reaction

Dandia, Anshu,Bansal, Sarika,Sharma, Ruchi,Rathore, Kuldeep S.,Parewa, Vijay

, p. 30280 - 30288 (2018/09/11)

A CuO NP decorated reduced graphene oxide (CuO NPs/rGO) composite was synthesized and characterized using various analytical techniques viz. XRD, TEM, SEM, UV-Vis, FT-IR, EDX, XPS and CV. The activity of the catalyst was probed for the Petasis-Borono-Mann

Multicomponent reaction in deep eutectic solvent for synthesis of substituted 1-aminoalkyl-2-naphthols

Azizi, Najmedin,Edrisi, Mahtab

, p. 379 - 385 (2017/01/14)

One-pot multicomponent synthesis of Betti bases (aminoalkyl naphthols) from aldehydes, β-naphthol, and secondary amines in deep eutectic solvent (DES) based on urea and choline chloride has been developed. A broad range of aminoalkyl naphthols can be obta

An efficient and green method for the synthesis of Betti base employing nano-SiO2–H3BO3 as a novel recyclable heterogeneous catalyst

Teimuri-Mofrad, Reza,Gholamhosseini-Nazari, Mahdi,Esmati, Somayeh,Shahrisa, Aziz

, p. 6845 - 6861 (2017/10/06)

Abstract: In this research, nano-SiO2–H3BO3 is introduced as a novel environmentally benign and recyclable heterogeneous catalyst for the synthesis of aminonaphthols under solvent-free conditions without an additional co-catalyst or additive in air. This synthesis method offers several advantages, such as a green and eco-friendly protocol, operational simplicity, mild reaction conditions, short reaction times, higher yields and easy work-up procedures. The work-up of these very clean reactions involves only recrystallization of the product from ethanol and recovery of the catalyst by filtration. The catalyst can be reused several times without losing activity.

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