609-85-8

Basic information

• Product Name: 2-Amino-3,5-dibromobenzoic acid
• Synonyms: Benzoic acid, 2-amino-3,5-dibromo-;RARECHEM AL BO 1185;BUTTPARK 89\07-50;3,5-DIBROMOANTHRANILIC ACID;3,5-DIBROMO-2-AMINOBENZOIC ACID;2-AMINO-3,5-DIBROMOBENZOIC ACID;2-Amino-3,5-dibromobenzoic acid, tech;3,5-DIBROMOANTHRANILIC ACID, 98+%
• CAS NO: 609-85-8
• Molecular Formula: C₇H₅Br₂NO₂
• Molecular Weight: 294.93
• EINECS: 1533716-785-6
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Acids & Esters;Anilines, Amides & Amines;Bromine Compounds;Aromatic Amino Acids;Unnatural Amino Acid Derivatives;Peptide Synthesis
• Mol File: 609-85-8.mol

Chemical Properties

• Melting Point: 235-236 °C(lit.)
• Boiling Point: 367.6 °C at 760 mmHg
• Flash Point: 176.1 °C
• Appearance: White to beige/Powder
• Density: 2.158 g/cm³
• Vapor Pressure: 4.74E-06mmHg at 25°C
• Refractive Index: 1.699
• PKA: 4.16±0.10(Predicted)
• BRN: 779291
• CAS DataBase Reference: 2-Amino-3,5-dibromobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3,5-dibromobenzoic acid(609-85-8)
• EPA Substance Registry System: 2-Amino-3,5-dibromobenzoic acid(609-85-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-37/38-36
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 609-85-8(Hazardous Substances Data)

Usage

Synthesis

A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid ?at 15 °С and the mixture was stirred for 1 h at the same temperature. The product ?was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids ?containing mixture (0.5 g) was added to 10 mL of boiling water followed by the ?addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum. ?The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate.?IR (suspension in nujol, cm?1 ): 3469, 3364, ?1682, 1600, 1564, 1538, 1454, 1421, 1378, 1328, 1307, 1226, 1063, 902, 882, 790, ?711, 691, 591, 543.

Chemical Properties

White to light yellow crystal powder

InChI:InChI=1/C7H5Br2NO2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2H,10H2,(H,11,12)

Upstream product

• 118-48-9 isatoic anhydride 
• 6374-91-0 5,7-Dibromoisatin 
• 40889-42-7 6,8-dibromo-2-methyl-3,1-benzoxazin-4(H)-one 
• 88-72-2 1-methyl-2-nitrobenzene 
• 60912-52-9 3,5-dibromo-2-nitro-benzoic acid 
• 68385-95-5 3,5-dibromoanthranilonitrile 
• 118-92-3 anthranilic acid 
• 2299-73-2 N,N-bis(4-methoxybenzylidene)hydrazine 
• 28867-76-7 benzaldehyde benzylidenehydrazone 
• 95-54-5 1,2-diamino-benzene 
• 54754-60-8 6-chloro-8-methyl-1H-3,1-benzoxazine-2,4-dione 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 40889-42-7 6,8-dibromo-2-methyl-3,1-benzoxazin-4(H)-one 
• 17518-85-3 6,8-dibromo-3,4-dihydro-4-oxo-quinazoline 
• 643-37-8 6,8-dibromoquinazoline-2,4-(1H,3H)-dione 
• 54754-60-8 6-chloro-8-methyl-1H-3,1-benzoxazine-2,4-dione 
• 618-58-6 3,5-dibromobenzoic acid 
• 6311-60-0 3,5-dibromonitrobenzene 
• 615-57-6 2,4-dibromo-aniline 
• 15719-64-9 methylammonium carbonate 
• 15396-38-0 2,3,5-tribromo-benzoic acid 
• 16524-04-2 2‐amino‐3,5‐dibromobenzamide 
• 15396-40-4 3,5-dibromo-2-iodo-benzoic acid 
• 114571-71-0 3,5-dibromo-phthalic acid 
• 58155-85-4 6,8-dibromo-2-styryl-benzo[d][1,3]oxazin-4-one 
• 73314-26-8 6,8-dibromo-2-(3,4,5-trimethoxy-phenyl)-benzo[d][1,3]oxazin-4-one 

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