76064-23-8

Basic information

• Product Name: Sodium 3-cyanoprop-1-enoxide
• CAS NO: 76064-23-8
• Molecular Weight: 91.0448
• Mol File: 76064-23-8.mol

Chemical Properties

• CAS DataBase Reference: Sodium 3-cyanoprop-1-enoxide(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 3-cyanoprop-1-enoxide(76064-23-8)
• EPA Substance Registry System: Sodium 3-cyanoprop-1-enoxide(76064-23-8)

Safety Data

• Hazardous Substances Data: 76064-23-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Sodium 3-cyanoprop-1-enoxide is used as a reagent for the formation of carbon-carbon bonds in organic synthesis. Its unique structure allows for the creation of new chemical linkages, facilitating the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, sodium 3-cyanoprop-1-enoxide is used as a key intermediate in the synthesis of various drugs. Its ability to form carbon-carbon bonds makes it a valuable component in the development of new medicinal compounds.
Used in Agrochemical Production:
Sodium 3-cyanoprop-1-enoxide is also utilized in the production of agrochemicals, such as pesticides and herbicides. Its role in creating carbon-carbon bonds is essential for the synthesis of these compounds, which are used to protect crops and enhance agricultural productivity.
Used in Dye Production:
In the dye industry, sodium 3-cyanoprop-1-enoxide is used as a starting material for the synthesis of various dyes. Its ability to form carbon-carbon bonds contributes to the creation of a wide range of colored compounds used in textiles, printing, and other applications.

Upstream product

• 124-38-9 carbon dioxide 
• 7440-44-0 pyrographite 
• 75-05-8 acetonitrile 
• 124-41-4 sodium methylate 
• 109-94-4 formic acid ethyl ester 
• 288-14-2 ISOXAZOLE 

Downstream Products

• 1021175-71-2 diethyl 2-(2-cyanovinylamino)malonate 
• 333-49-3 2-thiocytosine 
• 3289-47-2 4-amino-2-methoxypyrimidine 
• 2183-66-6 4-amino-2-(methylthio)pyrimidine 
• 54308-63-3 2-ethylsulfanyl-pyrimidin-4-ylamine 
• 60722-70-5 2-benzylsulfanyl-pyrimidin-4-ylamine 
• 71-30-7 Cytosine 
• 61310-53-0 3-ethoxyacrylonitrile 
• 2032-34-0 3,3-bis(ethyloxy)propanenitrile 

Relevant articles and documents

3 - Ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of synthetic method

The invention belongs to the field of medicinal chemistry, in particular to medicinal chemistry of the in the field of organic synthesis, more in particular to 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of synthetic method. The method uses acetonitrile with a ester alcohol under the action of the alkali metal salt, to obtain the intermediate compound II, then this compound II and then under the action of the phase transfer catalyst, with the sulfuric acid b b obtained by the target mixture compound I, namely 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture. The invention disclosed 3 - ethoxy acrylonitrile and 3, 3 - diethyl dimethoxypropionitrile is treated mixture of the synthetic method has low material cost, relatively mild reaction conditions, the operation is simple, the yield and the like, which is suitable for the industrial production, application of the method.

Method for synthesizing cytosine

The invention discloses a method for synthesizing cytosine. The method comprises the following steps: taking charcoal and carbon dioxide as raw materials, and obtaining mixed gas through one-pot reaction; directly reacting with acetonitrile under the action of alkali without separation; finally condensing and cyclizing with urea to obtain the cytosine. The method disclosed by the invention has the benefits that the raw materials are cheap and easy to obtain, the use of an expensive, toxic and harmless reagent is avoided, the use of dangerous and corrosive operation steps is avoided, and the environmental protection and the industrial production are facilitated. The method disclosed by the invention provides a new synthetic pathway for the cytosine and has a potential application prospect.

Synthesis and reactivity of pyrrolo[3,2-d][1,3]oxazine-2,4-dione. Access to new pyrrolo[3,2-e][1,4]diazepine-2,5-diones

A convenient synthesis of pyrrolo[3,2-d][1,3]oxazine-2,4-dione 4 is described and its reactivity towards various nucleophiles studied. The regioselective ring opening of anhydride 4 or its N-alkylated analog 25 in the presence of alanine or proline afforded, respectively, imidazolidinedione 22 and N-protected pyrrolo[3,2-e][1,4]diazepines 30 and 31 in a one-pot process. In a last part of this study, an alternative route to produce a library of eight non protected pyrrolo[3,2-e][1,4]diazepine-2,5-diones 35a-h is described to overcome the limited reactivity of anhydride 4.