96-07-1

Basic information

• Product Name: 2-isopropylcyclohexan-1-ol
• Synonyms: 2-isopropylcyclohexan-1-ol;2-Isopropylcyclohexanol;Ai3-17386;Cyclohexanol, 2-(1-methylethyl)-;Einecs 202-474-6;2-propan-2-ylcyclohexan-1-ol
• CAS NO: 96-07-1
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.23862
• EINECS: 202-474-6
• Mol File: 96-07-1.mol

Chemical Properties

• Boiling Point: 203.1°Cat760mmHg
• Flash Point: 80.8°C
• Appearance: /
• Density: 0.914g/cm³
• Vapor Pressure: 0.0684mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-isopropylcyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-isopropylcyclohexan-1-ol(96-07-1)
• EPA Substance Registry System: 2-isopropylcyclohexan-1-ol(96-07-1)

Safety Data

• Hazardous Substances Data: 96-07-1(Hazardous Substances Data)

Usage

Uses

Used in Fragrance Industry:
2-Isopropylcyclohexan-1-ol is used as an intermediate for the production of fragrances, contributing to the creation of various scent profiles in perfumes and other scented products.
Used in Flavor Industry:
In the flavor industry, 2-isopropylcyclohexan-1-ol serves as an intermediate, aiding in the development of distinct taste profiles for food and beverage products.
Used in Pharmaceutical Industry:
2-Isopropylcyclohexan-1-ol is utilized as an intermediate in the manufacturing of pharmaceuticals, playing a role in the synthesis of various medicinal compounds.
Used as a Solvent:
This chemical compound is also used as a solvent in various industrial applications, helping to dissolve other substances for processes such as chemical reactions or cleaning.
Used in Organic Compound Manufacturing:
2-Isopropylcyclohexan-1-ol is employed in the manufacturing of other organic compounds, serving as a building block for the synthesis of a range of chemical products.
Safety Note:
2-Isopropylcyclohexan-1-ol is flammable, and appropriate safety precautions should be taken during its storage, handling, and use to prevent accidents. While it is not considered a significant environmental pollutant or to have serious health effects, it should still be used with caution in a controlled industrial setting.

InChI:InChI=1/C9H18O/c1-7(2)8-5-3-4-6-9(8)10/h7-10H,3-6H2,1-2H3

Upstream product

• 88-69-7 2-(1-methylethyl)phenol 
• 286-20-4 cyclohexane-1,2-epoxide 
• 75-26-3 isopropyl bromide 
• 822-87-7 2-Chlorocyclohexanone 
• 64-17-5 ethanol 
• 1004-77-9 2-isopropylcyclohexanone 
• 64-19-7 acetic acid 
• 10488-25-2 cis-2-isopropylcyclohexan-1-ol 
• 555-31-7 aluminum isopropoxide 
• 67-63-0 isopropyl alcohol 
• 67-64-1 acetone 

Downstream Products

• 938-02-3 1-hydroxy-c-2-isopropyl-r-1-cyclohexanecarbonitrile 
• 938-02-3 1-hydroxy-c-2-isopropyl-r-1-cyclohexanecarbonitrile 
• 92729-19-6 2-Isopropyl-1-phenyl-cyclohexanol 
• 92650-76-5 6-Isopropyl-1-phenyl-cyclohexen-⁽¹⁾ 
• 10488-25-2 cis-2-isopropylcyclohexan-1-ol 
• 1236357-39-3 p-tolyl-carbamic acid 2-isopropyl-cyclohexyl ester 
• 1004-77-9 2-isopropylcyclohexanone 
• 1975-32-2 (R)-2-isopropylcyclohexanone 
• 98102-91-1 (R)(+)-1r-Isopropyl-cyclohexanol-(2t) 
• 98102-89-7 (-) Trans 2-isopropyl cyclohexanol 

Relevant articles and documents

Asymmetric Induction via a Helically Chiral Anion: Enantioselective Pentacarboxycyclopentadiene Br?nsted Acid-Catalyzed Inverse-Electron-Demand Diels-Alder Cycloaddition of Oxocarbenium Ions

An enantioselective catalytic inverse-electron-demand Diels-Alder reaction of salicylaldehyde acetal-derived oxocarbenium ions and vinyl ethers to generate 2,4-dioxychromanes is described. Chiral pentacarboxycyclopentadiene (PCCP) acids are found to be effective for a variety of substrates. Computational and X-ray crystallographic analyses support the unique hypothesis that an anion with point-chirality-induced helical chirality dictates the absolute sense of stereochemistry in this reaction.

NOVEL ORGANOLEPTIC COMPOUNDS

The present invention relates to novel compounds and their use as fragrance materials.

Cytochrome P450 catalyzed oxidative hydroxylation of achiral organic compounds with simultaneous creation of two chirality centers in a single C-H activation step

Regio- and stereoselective oxidative hydroxylation of achiral or chiral organic compounds mediated by synthetic reagents, catalysts, or enzymes generally leads to the formation of one new chiral center that appears in the respective enantiomeric or diastereomeric alcohols. By contrast, when subjecting appropriate achiral compounds to this type of C-H activation, the simultaneous creation of two chiral centers with a defined relative and absolute configuration may result, provided that control of the regio-, diastereo-, and enantioselectivity is ensured. The present study demonstrates that such control is possible by using wild type or mutant forms of the monooxygenase cytochrome P450 BM3 as catalysts in the oxidative hydroxylation of methylcyclohexane and seven other monosubstituted cyclohexane derivatives.

Diastereoselective reduction of cyclohexanones with diisobutylaluminium phenoxides in terms of the isoinversion principle

The diastereoselectivity of the reduction of 2-substituted cyclohexanones 1-6 with 4-substituted diisobutylaluminium phenoxides a-d has been investigated as a function of temperature. The high-temperature region is found to be dominated by hydride transfer, which is controlled by steric as well as electronic effects. However, at low temperatures the Meerwein-Ponndorf-Verley reaction gains in Importance. This phenomenon is quantified by an isoinversion relationship.

MMPP (Magnesium Monoperoxyphthalate) in acetonitrile; a new approach to the synthesis of lactones via Baeyer-Villiger oxidation of cyclic ketones

A variety of unsubstituted and mono- or di-substituted cycloalkanones can be oxidised with modest excess of magnesium monoperoxyphthalate hexahydrate in acetonitrile to produce the corresponding lactones in facile, selective, and high yielding manner.