13089-48-0

Basic information

• Product Name: N-Benzoylcytidine
• Synonyms: N(sup 4)benzoylcytidine;N4-Bz-rC;Bz-rC;NSC 242979;N-(1-(3,4-Dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyriMidin-4-yl)benzaMide;4N-Benzoyl Cytidine;N4-Benzoylcytidine;N-(1-(3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzam
• CAS NO: 13089-48-0
• Molecular Formula: C₁₆H₁₇N₃O₆
• Molecular Weight: 347.32
• EINECS: 2017-001-1
• Product Categories: Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Nucleotides;Nucleosides;Oligonucleotide Synthesis;Specialty Synthesis;Nucleotides and Nucleosides;Biochemistry;Nucleosides and their analogs
• Mol File: 13089-48-0.mol

Chemical Properties

• Melting Point: 230-234 °C (dec.)(lit.)
• Appearance: White to Off-white/Crystalline Powder
• Density: 1.59 g/cm³
• Refractive Index: 46 ° (C=1, DMSO)
• Storage Temp.: Store at 0°C
• Solubility: Soluble in 1N NaOH at 10mg/ml. Also soluble in methanol or DMSO
• PKA: 8.61±0.20(Predicted)
• CAS DataBase Reference: N-Benzoylcytidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzoylcytidine(13089-48-0)
• EPA Substance Registry System: N-Benzoylcytidine(13089-48-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 13089-48-0(Hazardous Substances Data)

Usage

Uses

Used in Oligoribonucleotide Synthesis:
N-Benzoylcytidine is used as a building block for the synthesis of oligoribonucleotides, which are essential in the development of various applications in molecular biology and pharmaceuticals. These oligoribonucleotides can be utilized in the creation of antisense molecules, RNA interference (RNAi) agents, and other therapeutic agents that target specific genes or RNA molecules for the treatment of various diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-Benzoylcytidine is used as a key component in the development of novel drugs and therapeutic agents. Its role in oligoribonucleotide synthesis allows for the creation of targeted treatments for a wide range of diseases, including cancer, genetic disorders, and viral infections.
Used in Molecular Biology Research:
N-Benzoylcytidine is also used in molecular biology research as a tool for studying the structure, function, and interactions of RNA molecules. Its incorporation into oligoribonucleotides enables researchers to investigate the mechanisms of gene regulation, RNA processing, and other cellular processes at the molecular level.

InChI:InChI=1/C16H17N3O6/c20-8-10-12(21)13(22)15(25-10)19-7-6-11(18-16(19)24)17-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,20-22H,8H2,(H,17,18,23,24)/t10-,12-,13-,15-/m1/s1

Upstream product

• 39946-94-6 4-N-benzoyl-2',3'-O-isopropylidenecytidine 
• 98-88-4 benzoyl chloride 
• 65-46-3 CYTIDINE 
• 93-97-0 benzoic acid anhydride 
• 147490-72-0 4-N-benzoyl-2'-O-<1-(2-fluorophenyl)-4-methoxypiperidin-4-yl>cytidine 
• 80015-55-0 2'-O-(4-methoxybenzyl)cytidine 
• 97626-95-4 N⁴-benzoyl-1-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)-cytosine 
• 65-85-0 benzoic acid 
• 1314034-30-4 N₄-benzoyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-O-(methoxymethyl)cytidine 
• 69304-43-4 1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-N⁴-benzoylcytosine 
• 118684-37-0 O^2',O^3',O^5'-tris-trimethylsilyl-N⁴-benzoylcytidine 
• 80015-59-4 2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine 
• 263009-01-4 4-N-Benzoyl-2'-O-[1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl]cytidine 

Downstream Products

• 52571-45-6 2'-O-methyl-N⁴-benzoylcytidine 
• 72409-20-2 N⁴-benzoyl-5'-O-(tert-butyldimethylsilyl)cytidine 
• 72429-31-3 N⁴-benzoyl-3',5'-di-O-tert-butyldimethylsilylcytidine 
• 72429-30-2 N⁴-benzoyl-2',5'-di-O-tert-butyldimethylsilylcytidine 
• 77772-57-7 N⁴-benzoyl-2',3'-O-(triphenylphosphoranediyl)-O²,5'-cyclocytidine 
• 104110-05-6 Thiophosphoric acid O-[(2R,3S,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester O',O''-bis-(4-nitro-phenyl) ester 
• 31505-94-9 N-[1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2-methoxy-2-methyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide 
• 72687-04-8 Acetic acid (2R,3R,4R,5R)-2-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl ester 
• 28224-89-7 O^3'-acetyl-N⁴-benzoyl-cytidine 
• 69304-43-4 1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-N⁴-benzoylcytosine 
• 82434-62-6 N-(1-{(2R,3R,4S,5R)-4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-hydroxy-tetrahydro-furan-2-yl}-2-oxo-1,2-dihydro-pyrimidin-4-yl)-benzamide 
• 82434-58-0 4-N-benzoyl-1-(2,5-O-bis-dimethoxytrityl-β-D-ribofuranosyl)cytosine 
• 81246-76-6 4-N-benzoyl-1-(5-O-dimethoxytrityl-β-D-ribofuranosyl)cytosine 
• 80015-59-4 2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine 

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