17599-61-0

Basic information

• Product Name: [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE
• Synonyms: [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE;(Benzylidene)(trimethylsilyl)amine;N-Trimethylsilylbenzaldimine;N-Trimethylsilylbenzaldimine 95%
• CAS NO: 17599-61-0
• Molecular Formula: C₁₀H₁₅NSi
• Molecular Weight: 177.3183
• Product Categories: Building Blocks;Chemical Synthesis;Imines/Amidines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 17599-61-0.mol
• Article Data: 38

Chemical Properties

• Boiling Point: 50-60 °C
• Flash Point: 49 °C
• Appearance: /
• Density: 1.444 g/mL at 25 °C
• Refractive Index: n20/D 1.521
• CAS DataBase Reference: [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE(17599-61-0)
• EPA Substance Registry System: [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE(17599-61-0)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 2
• Hazardous Substances Data: 17599-61-0(Hazardous Substances Data)

Usage

General Description

[1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE is a chemical compound with the molecular formula C11H15NSi. It is a silane compound, which is a type of organosilicon compound that contains a silicon atom bonded to carbon. This specific compound contains a phenyl group, a methylidene group, and three trimethylsilyl groups bonded to a central amine nitrogen atom. Silane compounds are commonly used in the production of silicones, as adhesion promoters, and in the formulation of coatings. Additionally, they are often used as intermediates in the synthesis of other organic and organometallic compounds. Overall, [1-PHENYL-METHYLIDENE]-TRIMETHYLSILANYL-AMINE has a range of potential applications in the field of chemistry and materials science.

Upstream product

• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 100-52-7 benzaldehyde 
• 75-77-4 chloro-trimethyl-silane 
• 16118-22-2 benzylidenamine 
• 13892-06-3 N-trimethylsilyl(triphenylphosphoranylidene)amine 
• 70582-00-2 1,1,1,3,3-pentamethyldisilazane 
• 100-47-0 benzonitrile 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 134390-13-9 2-(aminophenylmethyl)-N-methylbenzamide hydrochloride 
• 835-18-7 3-phenyl-2,3-dihydro-isoindol-1-one 
• 37800-54-7 N-Benzylideneacetamide 
• 121767-19-9 1-Phenyl-2-aza-3-trimethylsilyloxy-1,3-butadiene 
• 27593-61-9 methyl N-phenylmethylenecarbamate 
• 4383-23-7 1-phenyl-but-3-enylamine 
• 127236-28-6 (4S,4aR,7aR)-4,6-Diphenyl-2-[(E)-phenylimino]-tetrahydro-pyrrolo[3,4-e][1,3]thiazine-5,7-dione 
• 181294-24-6 (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 14856-79-2 N-benzyl(trimethylsilyl)amine 

Relevant articles and documents

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Photoactive spatial proximity probes for binding pairs with epigenetic marks

A new strategy for encoding polypeptide libraries with photolabile tags is developed. The photoassisted assay, based on conditional release of encoding tags only from bound pairs, can differentiate between peptides which have minor differences in a form o

Direct and practical Gilman-Speeter synthesis of 3,4-trisubstituted β-lactams via the Thorpe-Ingold effect

A highly efficient Gilman-Speeter synthesis of 3,4-trisubstituted β-lactams possessing a 4-aryl substituent is described, employing a direct, uncatalyzed Mannich reaction between TMS imines and TMS ketene acetals. The process avoids cryogenic conditions, making it more amenable to process-scale use than related methods for β-lactam synthesis. A Gilman-Speeter diastereoselective version using a sulfinyl imine and leading to homochiral sulfinyl β-aminoester is also presented.

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

The reaction of secondary homopropargylamines, isocyanides, and water in the presence of a catalytic amount of silver acetate and subsequent purification by chromatography on silica gel afforded substituted proline amides in good to excellent yields. Primary homopropargylamines underwent a cyclizative Ugi–Joullié three-component reaction with isocyanides and carboxylic acids to afford functionalized N-acyl proline amides. High diastereoselectivity was observed in the synthesis of 4-alkoxy and 4,5-disubstituted proline derivatives. This work represents the first examples of a three-component cyclizative 1,1-aminoacylation of terminal alkynes.