2088-35-9

Basic information

• Product Name: 1,1-dichlorocyclopropane
• Synonyms: Cyclopropane, 1,1-dichloro-; 1,1-Dichlorocyclopropane
• CAS NO: 2088-35-9
• Molecular Formula: C₃H₄Cl₂
• Molecular Weight: 110.9699
• EINECS: 218-231-2
• Mol File: 2088-35-9.mol

Chemical Properties

• Boiling Point: 109.3°C at 760 mmHg
• Flash Point: 33°C
• Density: 1.34g/cm³
• Vapor Pressure: 29.2mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: 1,1-dichlorocyclopropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dichlorocyclopropane(2088-35-9)
• EPA Substance Registry System: 1,1-dichlorocyclopropane(2088-35-9)

Safety Data

• Hazardous Substances Data: 2088-35-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1,1-dichlorocyclopropane is utilized as a chemical intermediate in the production of various compounds. Its reactivity makes it a valuable component in the synthesis of a range of organic molecules.
Used as a Solvent for Extraction:
In the field of chemistry, 1,1-dichlorocyclopropane serves as a solvent for extraction processes. Its properties allow for the efficient separation of substances, facilitating the isolation of specific compounds from mixtures.
Used as a Stripping Agent in Purification Processes:
1,1-dichlorocyclopropane is employed as a stripping agent in the purification of various materials. Its ability to selectively remove unwanted components contributes to the refinement of substances in different industries.
Used in Chemical Industry:
1,1-dichlorocyclopropane is used as a reactive intermediate for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatility in organic reactions is key to its application in this industry.
Used in Environmental and Safety Management:
Given its potential environmental and health hazards, 1,1-dichlorocyclopropane is also a subject of interest in environmental and safety management. It requires proper handling, storage, and disposal protocols to mitigate risks to both human health and the environment.

Upstream product

• 75-19-4 cyclopropane 
• 7732-18-5 water 
• 7782-50-5 chlorine 
• 765-30-0 Cyclopropylamine 
• 16156-53-9 isobutyl methanesulfonate 
• 715-11-7 2-tosyloxybutane 
• 74-85-1 ethene 
• 3294-58-4 phenyl(bromodichloromethyl)mercury 
• 1840-40-0 trichloromethyltrifluorosilane 
• 67-66-3 chloroform 

Downstream Products

• 7393-45-5 cyclopropyl chloride 
• 23153-23-3 1,1,1,3,3-pentachloropropane 
• 421-07-8 1,1,1-trifluoropropane 
• 421-02-3 1-chloro-1,1-difluoro-propane 
• 78-88-6 2,3-Dichloroprop-1-ene 
• 563-58-6 1,1-dichloropropene 
• 127-18-4 1,1,2,2-tetrachloroethylene 
• 67-72-1 hexachloroethane 
• 2065-35-2 hexachlorocyclopropane 
• 7789-89-1 1,1,1-trichloropropane 

Relevant articles and documents

Synthetic method and process of halogenated cyclopropane

The invention discloses a synthetic method and process of halogenated cyclopropane. The synthesis method and process comprise the following two steps of: (1) reacting cyclopropylamine serving as a rawmaterial with halogenated metal salt in the presence of nitrosation reagents such as nitrous acid ester to obtain 1, 1-dihalogenated cyclopropane; and (2) carrying out metallization reaction on the 1, 1dihalogenated cyclopropane and an organic metal reagent, and hydrolyzing to obtain halogenated cyclopropane. The synthesis method and process have the advantages that toxic reagents causing environmental pollution are not used, the purity and yield of the obtained product are high, and the synthesis method and process are suitable for industrial production.

BUTENE CONVERSION METHOD AND MONOFLUOROBUTANE PURIFICATION METHOD

Provided is an industrially simple and cheap method for efficiently removing butene from crude monofluorobutane containing butene without causing substantial decomposition, transformation, or the like of the monofluorobutane. In a provided monofluorobutane purification method, crude monofluorobutane containing butene is brought into contact with trihalomethane in the presence of an alkali aqueous solution to convert the butene to a compound having a higher boiling point than the monofluorobutane, water is subsequently added to a reaction mixture obtained thereby to dissolve a produced salt, an organic layer is separated, and then the separated organic layer is purified by distillation.

Kinetics of elementary reactions in the chain chlorination of cyclopropane

The kinetics of elementary reactions involved in the chain chlorination of cyclopropane were studied using a combination of absolute and relative rate constant measurements and first principles electronic structure calculations. Absolute rate coefficients for the reaction of Cl with cyclopropane were measured between 293 and 623 K by a laser-photolysis/CW infrared absorption method. To support the experimental investigations, first principles electronic structure calculations were performed. Vibrational spectra of c-C3H5Cl, c-C3H4Cl2, and c-C3H3Cl3 were calculated. Gem-C3H4Cl2 is calculated to be the kinetically and thermodynamically most favored dichlorocyclopropane. The computational results were consistent with a model in which gem-C3H4Cl2 is the predominant product of chlorination of C3H5Cl, and gem-C3H3Cl3 is the only product of chlorination of gem-C3H4Cl2. Chlorocyclopropane was ～ a factor of 10 times more reactive than cyclopropane toward chlorine atoms at 296 K and is converted into dichlorocyclopropane.

Solvent pressure effects in free radical reactions. 2. Reconciliation of the gas and condensed phase chlorination of cyclopropane

The results reported herein demonstrate that the chemoselectivity (SH2 ring opening vs abstraction of a cyclopropyl hydrogen) associated with the free radical chlorination of cyclopropane is solvent dependent. Internal pressure is implicated as the solvent parameter responsible for the observed solvent effect. (Solvents of high internal pressure favor the SH2 process; hydrogen abstraction becomes more important in solvents of low internal pressure or in the gas phase.) Extrapolation of the solution phase results to zero internal pressure accurately predicts the gas-phase result, suggesting that the difference in chemoselectivity between the vapor- and condensed-phase reactions is attributable to internal pressure in the condensed phase medium. No evidence for the chlorine atom cage effect is found in the chlorination of cyclopropane.

INFRARED LASER MULTIPHOTON ABSORPTION AND REACTION OF ORGANIC COMPOUNDS: SYNTHETICALLY UNIQUE REACTION CONTROL

Several examples of synthetically unique reaction controll effect by pulsed infrared laser multiphoton irradiation are reviewed.The uniqueness derives from the ability of the pulsed laser to rapidly vibrationally heat molecules coupled with an extremely short reaction time of approximately 10 μs for the processes discussed herein.Three systems are discussed: a bifunctional reactant with competing reaction channels, a reactant with consecutive reaction channels, and the free radical chlorination of cyclopropane.