2360-04-5Relevant articles and documents
PNN′ & P2NN′ ligands via reductive amination with phosphine aldehydes: synthesis and base-metal coordination chemistry
Gradiski, Matthew V.,Tsui, Brian T. H.,Lough, Alan J.,Morris, Robert H.
, p. 2150 - 2159 (2019)
Novel PNN′ & P2NN′ ligands based on 2-aminopyridine (APyPNN-R) R = Ph (1a), Cy (1b), iBu (1c), 8-aminoquinoline (AQPNN-R) R = Ph (2a), Cy (2b), iBu (2c), iPr (2d), and 2-picolylamine (P2NN-R) R = Ph (3a), Cy (3b), iBu (3c), have been synthesized via a versatile, one-pot, single-step, reductive amination of tertiary phosphine acetaldehydes with the amine by reaction with STAB (where STAB is sodium(triacetoxy)borohydride). Ligands 1b and 1c bridge between paramagnetic Co(ii) and form dimeric complexes Co2Cl4(APyPNN-R)2 (4 and 5) when reacted with cobalt dichloride. Ligands 2a-c coordinate in a tridentate fashion forming chelate complexes MCl2(AQPNN-R) M = Co(ii) (6-8), and, for 2d, the Fe(ii) complex FeCl2(AQPNN-iPr) (9). A solution magnetic susceptibility value for 9 of 3.9μB is consistent with a monomer-dimer equilibrium. The synthesis of the dimeric complex [FeCl2(AQPNN-Ph)]2 (10) using 2a as well as solid state magnetic susceptibility measurements on 9 and 10 confirm this phenomenon. Ligand 3a coordinates to Fe(ii) in an interesting tetradentate fashion despite bearing a tertiary amine moiety giving octahedral FeCl2(P2NN′) (11). All of the metal complexes have been characterized by elemental analysis, paramagnetic 1H NMR spectroscopy, solution magnetic susceptibility, and single crystal X-ray diffraction (XRD).
Self-immolative systems for the disclosure of reactive electrophilic alkylating agents
Acton, Aaron L.,Leroux, Flavien,Feula, Antonio,Melia, Kelly,Sambrook, Mark R.,Hayes, Wayne,Russell, Andrew T.
supporting information, p. 5219 - 5222 (2019/05/07)
In this paper we report the design, synthesis and assessment of the first examples of self-immolative systems triggered by non-acidic electrophilic agents such as methyl, allyl or benzylic halides. These systems provide a visual colorimetric disclosure response upon exposure to these electrophilic reagents under mild, basic conditions without the need for the use of analytical instrumentation.
Ruthenium-catalyzed regio- and enantioselective allylic substitution with water: Direct synthesis of chiral allylic alcohols
Kanbayashi, Naoya,Onitsuka, Kiyotaka
, p. 5197 - 5199 (2011/06/26)
Less is more: A new route to access chiral allylic alcohols through the regio- and enantioselective substitution of monosubstituted allylic chlorides with water has been developed. The reaction is catalyzed effectively by planar-chiral cyclopentadienyl ruthenium complexes (see scheme). Copyright
Synthese und Charakterisierung von Hydridotrispyrazolylborat-Heterobimetall-Komplexen mit Titan und Molybdaen
Ipaktschi, Junes,Sulzbach, Werner
, p. 287 - 302 (2007/10/02)
The reaction of TiCl4 with (C6H5)2P(CH2CH2O)nH (2) and K*)3BH> affords the complexes Tp*TiCl2(OCH2CH2)nP(C6H5)2 (n = 1-3) (3), Tp*TiCl2 (n = 1-3) (4) and Tp*Ti3 (n = 1-3) (5) which are then converted into the heterobinuclear complexes 8 and 9.Similarly, we succeeded in the synthesis of the heterobimetallacycles Tp*TiCl2Mo(CO)4 (13) and Tp*TiCl2Mo(CO)4 (14) by the use of (CO)4Mo2 (10) and (CO)4Mo2 (n = 1-2) (11).The shortest distance between Ti and Mo according to the crystal structure analysis is 5.393 Angstroem.
A Simple Synthesis and Some Synthetic Applications of Substituted Phosphide and Phosphinite Anions
Tsvetkov, E. N.,Bondarenko, N. A.,Malakhova, I. G.,Kabachnik, M. I.
, p. 198 - 208 (2007/10/02)
Based on data for the acidity relationship of phosphines and phosphinous acids and water in dimethyl sulfoxide and water, a simple method is reported for the generation of phosphide and phosphinite anions by the action of concentrated aqueous alkali on primary and secondary phosphines as well as phosphinous acids in dimethyl sulfoxide or other dipolar aprotic solvents.Alkylation of the anion yields secondary and tertiary phosphines, polyphosphines, functionally substituted phosphines as well as similarly substituted phosphine oxides.Phosphinous acids have beenalkylated in various solvents in two-phase systems containing concentrated aqueous alkali and tetrabutylammonium iodide as phase transfer catalyst.
THE 2-(DIPHENYLPHOSPHINO)ETHYL GROUP (DPPE) AS A NEW CARBOXYL-PROTECTING GROUP IN PEPTIDE CHEMISTRY
Chantreux, Dominique,Gamet, Jean-Paul,Jacquier, Robert,Verducci, Jean
, p. 3087 - 3094 (2007/10/02)
The use of 2-(diphenylphosphino)ethyl group for carboxyl-protection of amino acids or peptides is described.This group is easily introduced by esterification using 2-(diphenylphosphino)ethanol in the presence of dicyclohexylcarbodiimide and 4-(dimethylamino)pyridine.These Dppe esters are stable under the standard conditions for peptide synthesis.Deprotection is carried out under mild conditions by quaternisation using methyl iodide followed by a β-elimination induced by fluoride ion or potassium carbonate.
