40018-26-6 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 40018-26-6 differently. You can refer to the following data:
1. 2,5-Dihydroxy-1,4-dithiane has a sulfurous, meaty, toasted bread-like odor
2. white to yellowish crystalline powder
Uses
Different sources of media describe the Uses of 40018-26-6 differently. You can refer to the following data:
1. 1,4-Dithiane-2,5-diol is a hydroxylated dithiane derivative with phytogrowth-inhibitory and antibacterial activities.
2. 1,4-Dithiane-2,5-diol was used in the synthesis of:substituted tetrahydrothiophene derivatives2-amino-3-(arylsulfonyl)thiophenes, potential antiviral and antitumor agents
Aroma threshold values
Aroma characteristics at 0.1% EtoH: sulfurous, grilled meaty, pungent, brothy, eggy, heavy and rich,
toasted bread, tomato
Taste threshold values
Taste characteristics at 0.25 to 10 ppm: metallic, meaty savory chicken and beef, sulfurous,
egg-yolk-like
Synthesis Reference(s)
Synthetic Communications, 14, p. 483, 1984 DOI: 10.1080/00397918408059569
General Description
1,4-Dithiane-2,5-diol undergoes bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction with chalcones to afford trisubstituted tetrahydrothiophenes. It participates in diastereoselective [3+3] cycloaddition with azomethine imines catalyzed by 1,4-diazabicyclo[2.2.2]octane. It is a mercaptoacetaldehyde dimer and an efficient synthon for incorporating a thiol group to in situ generated nitroalkenes.
Check Digit Verification of cas no
The CAS Registry Mumber 40018-26-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,1 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40018-26:
(7*4)+(6*0)+(5*0)+(4*1)+(3*8)+(2*2)+(1*6)=66
66 % 10 = 6
So 40018-26-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H8O2S2/c5-3-1-7-4(6)2-8-3/h3-6H,1-2H2/t3-,4+
40018-26-6Relevant articles and documents
2-Mercaptoaldehyde dimers and 2,5-dihydrothiophenes from 1,3-oxathiolan-5-ones
McIntosh, John M.,Siddiqui, Maqbool A.
, p. 1872 - 1875 (2007/10/02)
Representative 1,3-oxathiolan-5-ones (6), prepared from 2-mercaptoacids, have been reduced to 2-mercaptoaldehydes 1 with diisobutylaluminum hydride.The aldehydes 1, which appear to exist in several dimeric forms, react with vinyltriphenylphosphonium bromide to give 2,5-dihydrothiophenes.