53316-57-7Relevant articles and documents
A facile one pot synthesis of pyrano[2,3-c]pyrazole derivatives under microwave irradiation
Zhou, Jian-Feng,Tu, Shu-Jiang,Zhu, Hui-Qin,Zhi, San-Jun
, p. 3363 - 3366 (2002)
A series of substituted pyrano[2,3-c]pyrazole derivatives were synthesized by the one pot reaction of aromatic aldehydes, malononitrile and 3-methyl-1-phenyl-2-pyrazolin-5-one under microwave irradiation in good yields.
HClO4-sio2 nanoparticles: An efficient and versatile catalyst for synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles
Sadeghi, Bahareh,Shirkhani, Mona,Hassanabadi, Alireza
, p. 112 - 114 (2015)
The reaction between aromatic aldehydes, malononitrile and 3-methyl-1-phenyl-2-pyrazoline-5-one catalysed by silica supported perchloric acid nanoparticles (HClO4-sio2 nanoparticles) in solvent H2O under reflux provided a
Synthesis and biological activities of some new phosphorus compounds containing pyranopyrazole moiety
Abdel-Monem, Wafaa R.,Abed-Kariem, Somaia M.,Alfaifi, Mohammad Y.,Ali, Tarik E.,Assiri, Mohammed A.,EL-Edfawy, Somaya M.,El-Shaaer, Hafez M.,Elbehairi, Serag Eldin I.,Hassanin, Noha M.,Shati, Ali A.
, p. 1119 - 1137 (2021/06/21)
A simple method for construction of functionalized pyranopyrazoles containing phosphoramide and phosphonate groups via one-pot reaction was achieved. The methodology depended on the reaction of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazol
Synthesis and in vitro antimicrobial, antioxidant, and antiproliferative activities of some new pyrano[2,3-c]pyrazoles containing 1,2-azaphospholes, 1,3,2-diazaphosphinines and phosphonate moieties
Ali, Tarik E.,Assiri, Mohammed A.,El-Shaaer, Hafez M.,Abdel-Kariem, Somaia M.,Abdel-Monem, Wafaa R.,El-Edfawy, Somaya M.,Hassanin, Noha M.,Shati, Ali A.,Alfaifi, Mohammad Y.,Elbehairi, Serag Eldin I.
supporting information, p. 2478 - 2497 (2021/06/30)
New 1,2-azaphosphole, 1,3,2-diazaphosphinine, and phosphonate derivatives containing pyrano[2,3-c]pyrazole moiety were achieved. The synthetic pathways depended on the reaction of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile with some phosphorus reagents such as diethyl phosphite, phosphorus sulfides, and phenyl phosphorus halides under different conditions. Compounds 6 and 7 recorded potent antibacterial and antifungal activities with lower toxicity, while compounds 4 and 6 displayed promising antioxidative properties. Further, compounds 4 and 9 exhibited potent cytotoxic effects against MCF-7, HepG-2, and HCT-116 cancer cells. The early apoptotic cell death was observed by the compounds in all types of the treated cells. Compounds 3, 5, 7, 10, and 14 recorded low to moderate percentages of necrosis and late apoptosis toward all treated cells.
Catalyst-free UV365-assisted synthesis of pyran annulated heterocyclic scaffolds and evaluation of their antibacterial activities
Dutta, Arup,Rahman, Noimur,Kumar, John Elisa,Rabha, Jintu,Phukan, Tridip,Nongkhlaw, Rishanlang
supporting information, p. 263 - 278 (2020/11/03)
A convenient and eco-friendly, one-pot synthetic protocol for pharmaceutically important pyran-based heterocyclic compounds is repeated herein. The reactions were carried out at room temperature in a water–ethanol solvent mixture under direct irradiation
Zn (II)-Schiff base covalently anchored to CaO@SiO2: A hybrid nanocatalyst for green synthesis of 4H-pyrans
Sameri, Fatemeh,Bodaghifard, Mohammad Ali,Mobinikhaledi, Akbar
, (2021/08/03)
In this study, the Zn (II)-Schiff base covalently anchored onto the surface of CaO@SiO2 nanoparticles. The structure of this hybrid nanomaterial (CaO@SiO2-NH2-Sal-Zn) was characterized using the analytical techniques such
Tungstic acid (H4WO5) immobilized on magnetic-based zirconium amino acid metal–organic framework: An efficient heterogeneous Br?nsted acid catalyst for l-(4-phenyl)-2,4-dihydropyrano[2,3c]pyrazole derivatives preparation
Khademi, Shima,Zahmatkesh, Saeed,Aghili, Alireza,Badri, Rashid
, (2021/02/12)
A new magnetic nanocatalyst based on the immobilization of tungstic acid onto new design robust, cost-effective, green, and scalable zirconium-L-aspartate amino acid metal–organic framework (MOF)-grafted L-(+)-tartaric acid stabilized magnetite nanopartic
Sugarcane Bagasse Ash-Based Silica-Supported Boric Acid (SBA-SiO2-H3BO3): A Versatile and Reusable Catalyst for the Synthesis of 1,4Dihydropyrano[2,3c]pyrazole Derivatives
Kumar, A.,Pandey, A. K.,Shrivastava, S. C.
, p. 653 - 660 (2021/06/02)
Abstract: A simple, green, and efficient protocol has been developed for the synthesis of biologically active 1,4dihydropyrano[2,3c]pyrazole derivatives via one-pot four-component reaction of various substituted benzaldehydes, hydrazine hydrate or phenylh
Synthesis, characterization and application of Fe3O4@SiO2@CPTMO@DEA-SO3H nanoparticles supported on bentonite nanoclay as a magnetic catalyst for the synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles
Eftekhari far, Behrouz,Nasr-Esfahani, Masoud
, (2020/01/25)
Fe3O4 nanoparticles were prepared and decorated on the surface of nanobentonite (NB), and subsequently modified by the organic and inorganic linkers and then sulfonic acid immobilization on the nanoparticles. The NB-Fe3Os
Synthesis of some novel antimicrobial and antioxidant agents of functionalized pyrazolo[4',3':5,6]pyrano[3,2-d]-[1,2]azaphospholes and pyrazolo[4',3':5,6]pyrano[2,3-d]-[1,3,2]diazaphosphinines
Abdel-Kariem, Somaia M.,Abdel-Monem, Wafaa R.,Ali, Tarik E.,El-Edfawy, Somaya M.,El-Shaaer, Hafez M.,Hassanin, Noha M.
, p. 1902 - 1913 (2020/11/19)
We have demonstrated facile synthetic approach for some novel functionalized pyrazolo[4',3':5,6]pyrano[3,2-d][1,2]azaphospholes and pyrazolo-[4',3':5,6]pyrano[2,3-d][1,3,2]diazaphosphinines via treatment of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[
