57303-46-5

Basic information

• Product Name: 1H-Pyrazol-5-ol, 4,4'-(phenylmethylene)bis[3-methyl-1-phenyl-
• CAS NO: 57303-46-5
• Molecular Formula: C27H24N4O2
• Molecular Weight: 436.513
• Mol File: 57303-46-5.mol
• Article Data: 79

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-5-ol, 4,4'-(phenylmethylene)bis[3-methyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-5-ol, 4,4'-(phenylmethylene)bis[3-methyl-1-phenyl-(57303-46-5)
• EPA Substance Registry System: 1H-Pyrazol-5-ol, 4,4'-(phenylmethylene)bis[3-methyl-1-phenyl-(57303-46-5)

Safety Data

• Hazardous Substances Data: 57303-46-5(Hazardous Substances Data)

Upstream product

• 53316-57-7 6-amino-1,4-dihydro-3-methyl-1,4-diphenylpyrano[2,3-c]pyrazole-5-carbonitrile 
• 75-15-0 carbon disulfide 
• 4005-51-0 [1,3,4]Thiadiazol-2-ylamin 
• 39143-05-0 (Z)-4-benzylidene-3-methyl-1-phenyl-1H-pyrazolidinyl-5(4H)-ketone 
• 100-63-0 phenylhydrazine 
• 110-89-4 piperidine 
• 100-52-7 benzaldehyde 
• 89-25-8 edaravone 
• 27420-41-3 2-hydroxy-4H-pyrido<1,2-a>pyrimidin-4-one 
• 1137-96-8 N-(benzylidene)aniline N-oxide 
• 105-45-3 acetoacetic acid methyl ester 
• 141-97-9 ethyl acetoacetate 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 23901-60-2 4-benzylidene-3-methyl-1-phenylpyrazolone 

Downstream Products

• 23901-60-2 4-benzylidene-3-methyl-1-phenylpyrazolone 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 

Relevant articles and documents

Synthesis of some new fused and binary 1,3,4-thiadiazoles as potential antitumor and antioxidant agents

Annulations of 2-amino-1,3,4-thiadiazole (1) with α,β- unsaturated carbonyl compounds 2, 5, and 9 afforded thiadiazolo[3,2-a]pyrimidin 3, benzamide 7, and bis-pyrazole derivative 11. Cyclization of benzamide 7 with POCl3 gave binary imidazole derivative 8. Moreover, alkylation of 1 with 2-bromo-1-(2H-chromen-3-yl) ethanone (9) followed by cyclization gave imidazo[2,1-b]-1,3,4-thiadiazole derivative 15. Multicomponent reaction of 1 with heterocyclic and/or aromatic aldehyde and thioglycolic acid afforded the corresponding thiazolidinones 17 and 19. Finally, a one-pot synthesis of 1 with isatin and thiosemicarbazide furnished the spirotriazole 20. The newly synthesized compounds were evaluated as antitumor agents.

Synthesis and evaluation of biological activities of bis(Spiropyrazolone)cyclopropanes: A potential application against Leishmaniasis

This work focuses on the search and development of drugs that may become new alternatives to the commercial drugs currently available for treatment of leishmaniasis. We have designed and synthesized 12 derivatives of bis(spiropyrazolone)cyclopropanes. We

Zirconium@guanine@MCM-41 nanoparticles: An efficient heterogeneous mesoporous nanocatalyst for one-pot, multi-component tandem Knoevenagel condensation–Michael addition–cyclization Reactions

MCM-41-supported nanoscale guanine bonded with Zr (IV) was prepared using sol–gel method and characterized by FT-IR, Raman, XRD, BET, TGA, EDX, ICP, AAS, X-Ray mapping, SEM and TEM techniques. This compound was employed as an efficient, chemoselectivity a