5332-73-0Relevant articles and documents
Preparation method of 3-methoxypropylamine
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Paragraph 0047; 0050-0052; 0054-0055; 0057-0058; 0060; ..., (2021/06/23)
The invention discloses a preparation method of 3-methoxylpropylamine. The method comprises the following steps: carrying out addition on methanol and acrylonitrile to prepare a 3-methoxylpropionitrile crude product, and then carrying out catalytic hydrogenation on the crude product by using a Raney catalyst to prepare the 3-methoxylpropylamine. In the addition reaction, through air protection and gradient temperature reaction control, the acrylonitrile conversion rate of the addition reaction can be increased, generation of hydrogenation reaction by-products is reduced, the acrylonitrile conversion rate is larger than 99.6%, the yeild of the 3-methoxylpropylamine is larger than 99.1% and residual quantity of acrylonitrile in the crude product is smaller than 0.3%; and the hydrogenation reaction raw materials do not need to be refined, an alkaline auxiliary agent does not need to be additionally added, the average yield of MOPA can reach 96.5%, and the catalyst can be recycled for more than 30 batches.
Preparation method of gamma-methoxypropylamine
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Paragraph 0029-0033; 0038-0042; 0047-0050; 0056-0060, (2019/03/28)
The invention provides a preparation method of gamma-methoxypropylamine, which is high in conversion rate. The invention adopts the following technical scheme: the preparation method of the gamma-methoxypropylamine, comprising the following steps: preparing 3-methoxypropionitrile by using acrylonitrile and sodium methoxide as raw materials; and by taking the 3-methoxypropionitrile as a raw material, preparing the gamma-methoxypropylamine in the presence of an amine reagent, a nickel catalyst and silver nitrate in a reducing manner. The raw materials are high in utilization rate; the separationprocess is simple and clear; the energy consumption is low; the production cost of a product is low; and the solvent and the catalyst can be recycled for use.
Method for preparing amino ether compounds
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Paragraph 0056; 0059; 0060, (2017/08/26)
The invention belongs to the technical field of organic synthesis and relates to a method for preparing amino ether compounds. The method comprises the following steps: by taking amino alcohol as a raw material, protecting amino in the amino alcohol so as to obtain Schiff base; carrying out an etherification reaction on the hydroxyl group in the Schiff base; and finally, performing amino deprotection, thereby obtaining corresponding amino ethers. The method disclosed by the invention has high regio-selectivity, the substrates of higher than 99.9% are subjected to etherification reaction, the reaction conversion ratio of each step is higher than 99.8%, and the total yield is higher than 95%; when amino alcohol is chiral, the amino ethers with retention of configuration can be obtained; and moreover, each step of the method is a conventional operation, the process cost is low, and three wastes are few, the energy consumption is low, an environment-friendly effect is achieved, and large-scale industrial production is easily realized.
Orthogonal breaking and forming of dynamic covalent imine and disulfide bonds in aqueous solution
Bracchi, Michael E.,Fulton, David A.
supporting information, p. 11052 - 11055 (2015/07/02)
Orthogonal bond-breaking and forming of dynamic covalent disulfide and imine bonds in aqueous solution is demonstrated. Through judicious choice of reaction partners and conditions, it is possible to cleave and reform selectively these bonds in the presence of each other in the absence of unwanted competing processes.
2-aminopyridine derivatives and combinatorial libraries thereof
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, (2008/06/13)
The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.
Process for the preparation of 2-nitrobenzaldehydes
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, (2008/06/13)
The new process for the preparation of 2-nitrobenzaldehydes of the general formula STR1 in which X1 and X2 either independently of one another represent hydrogen or halogen or one of the substituents represents nitro and the other substituent then represents hydrogen, by oxidation of 2-nitrotoluenes of the general formula STR2 in which X1 and X2 have the meaning indicated above is characterized in that the oxidation with oxygen or an oxygen-containing gas is carried out in the presence of at least one alkoxyalkylamine as a solvent and in the presence of strong bases.
Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety
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, (2008/06/13)
Reactive dyes of the formula STR1 in which D is the radical of an organic dye of the monoazo, polyazo, metal complex azo, anthraquinone, phthalocyanine, formazan, azomethine, dioxazine, phenazine, stilbene, triphenylmethane, xanthene, thioxanthrone, nitroaryl, naphthoquinone, pyrenequinone or perylenetetracarbimide series, R is hydrogen or substituted or unsubstituted C1-4 -alkyl, X is a substituent which is detachable as an anion, B is a radical of the formula STR2 R1 and R2, independently of each other, are hydrogen or substituted or unsubstituted C1-4 -alkyl or phenyl, A is a substituted or unsubstituted aliphatic or aromatic bridge member, Y is a --CO--Z or --SO2 --Z radical, Z is an aliphatic, aromatic or heterocyclic reactive radical, and n is 1 or 2, are suitable for dyeing or printing cellulose-containing and nitrogen-containing materials and in high dyeing yield produce dyeings and prints having good fastness properties.
Fiber-reactive disazo brown dye having vinylsulfone-type reactive group
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, (2008/06/13)
A compound, or a salt thereof, represented by the following formula, STR1 wherein A is a substituted or unsubstituted phenylene or naphthylene group, B is STR2 in which R3 is a hydrogen atom or a lower alkyl, lower alkoxy, acylamino or ureido group, and R4 is a hydrogen atom or a lower alkyl or lower alkoxy group, R1 and R3 are independently a hydrogen atom or a substituted or unsubstituted lower alkyl group, X is a substituted or unsubstituted amino, lower alkoxy, substituted phenoxy or sulfo group, Y is --SO2 CH=CH2 or --SO2 CH2 CH2 Z, in which Z is a group capable of being split by the action of an alkali, and m is 2 or 3, which is useful for dyeing hydroxyl group- or amide group-containing fiber materials to give dyed products of a brown color having excellent fastness properties with good build-up property.
The influence of a base on the methylation of aminoalchols
Kashima, Choji,Harada, Kazuo,Omote, Yoshimori
, p. 288 - 290 (2007/10/02)
A selective methylation towards N and O atoms on aminoalcohols was observed using metal hydride reagents as the base, and the predominant factors for the selectivity were investigated in detail.
Fibre-reactive dyes, containing both chloro and fluoro triazine radicals
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, (2008/06/13)
Fibre-reactive dyes of the formula STR1 wherein D is the radical of a benzene or naphthalene azo dye which contains sulpho groups, each of R1, R2 and R3 is a hydrogen atom, B is an arylene group and A is an amino group.
