622-36-6Relevant articles and documents
6-Heteroarylpyridoindolone Derivatives, Their Preparation and Therapeutic Use Thereof
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Page/Page column 13, (2008/12/04)
The disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing the same and therapeutic use thereof.
Piperazine derivatives as therapeutic agents
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, (2008/06/13)
Substituted piperazine compounds of formula I STR1 in which HET is a substituted pyrazole, imidazole or 1,2,4-triazole have utility in the treatment of central nervous system disorders, for example depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, Parkinson's disease, obesity, hypertension, Tourette's syndrome, sexual dysfunction, drug addiction, drug abuse, cognitive disorders, Alzheimer's disease, senile dementia, obsessive-compulsive behaviour, panic attacks, social phobias, eating disorders and anorexia, cardiovascular and cerebrovascular disorders, non-insulin dependent diabetes mellitus, hyperglycaemia, constipation, arrhythmia, disorders of the neuroendocrine system, stress, prostatic hypertrophy, and spasticity.
Regioselective Synthesis of 1-Alkyl-1-phenylhydrazines, 2-Alkyl-1-phenylhydrazines, and 1,2-Dialkyl-1-phenylhydrazines
Barluenga, Jose,Merino, Isabel,Vina, Sara,Palacios, Francisco
, p. 398 - 400 (2007/10/02)
1,2- and 1,1-disubstituted and 1,1,2-trisubstituted hydrazines are obtained by reaction of (2-phenylhydrazino)triphenylphosphonium bromide with butyllithium, followed by addition of alkyl halides and alkaline hydrolysis.