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Cas Database

6284-40-8

6284-40-8

Identification

  • Product Name:D-Glucitol,1-deoxy-1-(methylamino)-

  • CAS Number: 6284-40-8

  • EINECS:228-506-9

  • Molecular Weight:195.216

  • Molecular Formula: C7H17NO5

  • HS Code:2922.19

  • Mol File:6284-40-8.mol

Synonyms:Glucitol,1-deoxy-1-(methylamino)-, D- (8CI);Sorbitol, 1-deoxy-1-methylamino- (6CI);1-Deoxy-1-(methylamino)-D-glucitol;D-(-)-N-Methylglucamine;Meglumin;Meglumine;Methylglucamin;Methylglucamine;N-Methyl-D(-)-glucamine;N-Methylglucamine;N-Methylsorbitylamine;NSC 52907;NSC 7391;

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Safety information and MSDS view more

  • Signal Word:Danger

  • Hazard Statement:H318 Causes serious eye damage

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Usbiological
  • Product Description:N-Methyl-D-glucamine
  • Packaging:250g
  • Price:$ 322
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:Meglumine
  • Packaging:10g
  • Price:$ 120
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:N-Methyl-D-glucamine >99.0%(T)
  • Packaging:500g
  • Price:$ 69
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:N-Methyl-D-glucamine >99.0%(T)
  • Packaging:25g
  • Price:$ 17
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:N-Methyl-D-glucamine
  • Packaging:50 g
  • Price:$ 23
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:N-Methyl-D-glucamine 99.0-100.5% (titration)
  • Packaging:500g
  • Price:$ 102
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:N-Methyl-D-glucamine 99.0-100.5% (titration)
  • Packaging:1kg
  • Price:$ 206
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Meglumine meets USP testing specifications
  • Packaging:500g
  • Price:$ 204
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Meglumine European Pharmacopoeia (EP) Reference Standard
  • Packaging:
  • Price:$ 190
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:N-Methyl-D-glucamine European Pharmacopoeia (EP) Reference Standard
  • Packaging:y0001209
  • Price:$ 190
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 29 Articles be found

Method for synthesizing meglumine through catalytic hydrogenation by taking ammonia borane as hydrogen source

-

Paragraph 0020-0022; 0025, (2018/10/19)

The invention discloses a method for synthesizing meglumine through catalytic hydrogenation by taking ammonia borane as a hydrogen source, and belongs to the technical field of chemical drug synthesis. The method comprises the step that on the basis that glucose-methylamine schiff base is synthesized by taking glucose and methylamine as raw materials, and by taking ammonia borane as the hydrogen source for performing catalytic hydrogenation, the meglumine is synthesized. Compared with a method in the past, the method has the advantages of being mild in catalytic hydrogenation reaction, safe and high yield.

Low-Temperature Reductive Aminolysis of Carbohydrates to Diamines and Aminoalcohols by Heterogeneous Catalysis

Pelckmans, Michiel,Vermandel, Walter,Van Waes, Frederik,Moonen, Kristof,Sels, Bert F.

, p. 14540 - 14544 (2017/10/23)

Short amines, such as ethanolamines and ethylenediamines, are important compounds in today's bulk and fine chemicals industry. Unfortunately, current industrial manufacture of these chemicals relies on fossil resources and requires rigorous safety measures when handling explosive or toxic intermediates. Inspired by the elegant working mechanism of aldolase enzymes, a novel heterogeneously catalyzed process—reductive aminolysis—was developed for the efficient production of short amines from carbohydrates at low temperature. High-value bio-based amines containing a bio-derived C2 carbon backbone were synthesized in one step with yields up to 87 C%, in the absence of a solvent and at a temperature below 405 K. A wide variety of available primary and secondary alkyl- and alkanolamines can be reacted with the carbohydrate to form the corresponding C2-diamine. The presented reductive aminolysis is therefore a promising strategy for sustainable synthesis of short, acyclic, bio-based amines.

Mixed Sugar Compositions

-

Paragraph 0207, (2014/09/29)

Novel mixtures of sugar amides or sugar amines are disclosed that have improved thermal properties over the individual components. New feedstocks based on both the surfactant tail as well as the sugar head group allow for improved physical properties of sugar amide surfactant mixtures and thus improved formulatability. Furthermore, new sources of unique methyl esters from both bioengineering and or co-metathesis of fats and oils provide novel and improved sugar amide surfactant mixtures.

An efficient renewable-derived surfactant for aqueous esterification reactions

Rajabi, Fatemeh,Luque, Rafael

, p. 5152 - 5155 (2014/01/23)

An efficient and simple approach for the aqueous esterification of a range of carboxylic acids with alcohols has been developed using catalytic amounts of a glucose-derived N-alkanoyl-N-methyl-1-glycamine non-ionic biosurfactant (C12MG). Excellent yields to final products were obtained under mild conditions and the protocol was amenable to both aromatic and long alkyl chain acids (e.g. fatty acids).

Composition and Tablet Comprising Raltegravir

-

, (2012/12/14)

The present invention relates to a composition and tablet comprising raltegravir and to a process for the preparation of such tablet.

Process route upstream and downstream products

Process route

D-glucose
50-99-7

D-glucose

methylamine
74-89-5

methylamine

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
With hydrogen; In water; at 10 - 100 ℃; for 21.5h; under 5171.62 - 25858.1 Torr;
62.5%
With nickel kieselguhr; water; at 95 - 120 ℃; under 36775.4 - 102971 Torr; Hydrogenation;
With ethanol; Hydrierung des Reaktionsprodukts an Palladium-Kohle in Methanol bei 60grad/20-25at;
With hydrogen; nickel;
With hydrogen;
With nickel kieselguhr; water; at 95 - 120 ℃; under 36775.4 - 102971 Torr; Hydrogenation;
N-methyl-D-gluconamide
24758-59-6

N-methyl-D-gluconamide

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
With ammonia borane; palladium/alumina; at 78 ℃; for 2h; under 975.098 - 48004.8 Torr; Temperature; Pressure; Reagent/catalyst; Inert atmosphere; Large scale;
69.3%
D-glucose
50-99-7

D-glucose

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
With methylamine;
D-glucose
50-99-7

D-glucose

methylamine
74-89-5

methylamine

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

N,N`-dimethylethylenediamine
110-70-3

N,N`-dimethylethylenediamine

Conditions
Conditions Yield
With 5 wt% ruthenium/carbon; hydrogen; In water; at 124.84 ℃; for 1h; under 56255.6 Torr;
magnesium stearate
557-04-0

magnesium stearate

poloxamer

poloxamer

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
D-glucose
50-99-7

D-glucose

methylaminomethanol
3400-38-2

methylaminomethanol

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
pheophorbide-a

pheophorbide-a

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
D-Glucose
2280-44-6

D-Glucose

methylamine
74-89-5

methylamine

Conditions
Conditions Yield
With hydrogen; nickel; In water; at 48 - 100 ℃; for 3.33333h; under 52505.3 - 71257.1 Torr;
D-glucose
50-99-7

D-glucose

methylamine
74-89-5

methylamine

1-deoxy-1-(methylamino)-D-glucitol
6284-40-8,97780-33-1

1-deoxy-1-(methylamino)-D-glucitol

Conditions
Conditions Yield
With hydrogen; In water; at 10 - 100 ℃; for 21.5h; under 5171.62 - 25858.1 Torr;
62.5%
With nickel kieselguhr; water; at 95 - 120 ℃; under 36775.4 - 102971 Torr; Hydrogenation;
With ethanol; Hydrierung des Reaktionsprodukts an Palladium-Kohle in Methanol bei 60grad/20-25at;
With hydrogen; nickel;
With hydrogen;
With nickel kieselguhr; water; at 95 - 120 ℃; under 36775.4 - 102971 Torr; Hydrogenation;

Global suppliers and manufacturers

Global( 227) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Simagchem Corporation
  • Business Type:Manufacturers
  • Contact Tel:+86-592-2680277
  • Emails:sale@simagchem.com
  • Main Products:110
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Manufacturers
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
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