683-98-7Relevant articles and documents
Photo-triggered self-catalyzed fluoroalkylation/cyclization of unactivated alkenes: Synthesis of quinazolinones containing the CF2R group
Yang, Jin,Sun, Bin,Ding, Hao,Huang, Pan-Yi,Tang, Xiao-Li,Shi, Rong-Cheng,Yan, Zhi-Yang,Yu, Chuan-Ming,Jin, Can
supporting information, p. 575 - 581 (2021/01/28)
A novel photo-triggered self-catalyzed fluoroalkylation/cyclization of quinazolinones containing unactivated alkenes with various fluoroalkyl bromides has been developed. This transformation exhibits excellent substrate generality with respect to both the coupling partners. Of note is that this is the first example describing the Csp3-Br bond homolysis of alkyl bromides via a substrate (quinazolinones) induced energy transfer process. Additionally, the mild conditions, tolerance to a wide range of functional groups and operational simplicity make this protocol practical for the synthesis of fluorine-containing ring-fused quinazolinones. This journal is
Ozone oxidation process of preparing a halogenated acetic acid and esters thereof (by machine translation)
-
Paragraph 0078-0080, (2017/06/29)
The invention belongs to the field of chemical synthesis, in particular to a halogenated acetic acid or a halogenated acetic acid ester compound preparation method; halogenated ethane (type I) by ozone oxidation after the reaction, the reaction with water or alcohol to obtain a halogenated acetic acid or halogenated acetate (type II). (by machine translation)
Electrophilic addition reactions of 1,1-difluoro-2,2-diphenylthioethylene
Purrington, Suzanne T.,Sheu, Kuen-Wanq
, p. 165 - 168 (2007/10/02)
Electrophiles have been shown to add to F2C=C(SPh)2 at the difluoromethylene carbon, indicating that sulfur is better able to stabilize a positive charge than fluorine.
(METHYL DIFLUOROACETATE)COPPER REAGENT. REMARKABLE SOLVENT EFFECT ON THE 19F-NMR SPECTRUM, STABILITY AND REACTIVITY
Kitagawa, Osamu,Taguchi, Takeo,Kobayashi, Yoshiro
, p. 389 - 392 (2007/10/02)
The 19F-NMR spectrum, thermal stability and reactivity of (methyl difluoroacetate)copper reagent were found to differ remarkably depending on the solvent (DMSO, DMF, or HMPA) used.With allylic bromide or alkynyl halide a crucial solvent effect for the coupling reactions was observed.