Tscherniac-Einhorn Reaction

J. Tscherniac, DE 134979; A. Einhorn et al., Ann. 343, 207 (1905); 361, 113 (1908).

Introduction of the amidomethyl group into aromatic rings or activated methylene groups in the presence of sulfuric acid:



Reviews: R. Schröter, Houben-Weyl 11/1, 795 (1957); Hellman Angew. Chem. 69, 463 (1957); H. E. Zaugg, W. B. Martin, Org. React. 14, 52 (1965); H. E. Zaugg et al., J. Org. Chem. 34, 11, 14 (1969); K. Bott, Ber. 106, 2513 (1973); A. R. Mitchell et al., Tetrahedron Letters 1976, 3795.