Suarez Reaction (Suarez Fragmentation)

J. I. Concepion et al., Tetrahedron Letters 25, 1953 (1984); eidem, J. Org. Chem. 51, 402 (1986).

Photoinduced conversion of hydroxyl-containing substrates with hypervalent iodine I(III)I₂ to the corresponding oxygen-centered radical:



P. De Armas et al., Angew. Chem. Int. Ed. 31, 772 (1992). Mechanistic studies: J. L. Courtneidge et al., Tetrahedron Letters 35, 1003 (1994); T. Muraki et al., J. Chem. Soc. Perkin Trans. I 1999, 1713. Synthetic applications: C. M. Hayward et al., Tetrahedron Letters 34, 3989 (1993); A. Kittaka et al., Tetrahedron 55, 5319 (1999).