Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
Desoxymethyltesterone |
EINECS | N/A |
CAS No. | 3275-64-7 | Density | 1.02 g/cm3 |
PSA | 20.23000 | LogP | 4.94620 |
Solubility | N/A | Melting Point |
144-146 °C |
Formula | C20H32O | Boiling Point | 378.783 °C at 760 mmHg |
Molecular Weight | 288.473 | Flash Point | 160.866 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
5α-Androst-2-en-17b-ol, 17-methyl- (7CI,8CI);17-Methyl-5-α-androst-2-en-17-β-ol;Madol;Ba 2665;17α-Methylandrost-2-en-17β-ol;17α-Methyl-5α-androst-2-en-17β-ol;17α-Methyl-17β-hydroxy-5α-androst-2-ene;17-Methyl-5α-androst-2-en-17b-ol;NSC 63329; |
Article Data | 13 |
5α-androst-2-en-17-one
methylmagnesium bromide
17β-hydroxy-17α-methyl-5α-androst-2-ene
Conditions | Yield |
---|---|
In tetrahydrofuran at 0 - 20℃; Inert atmosphere; | 39% |
In diethyl ether; benzene |
2α-bromo-17β-hydroxy-5α-androstan-3-one
17β-hydroxy-17α-methyl-5α-androst-2-ene
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: (i) NaBH4, EtOH, (ii) Zn, AcOH, (iii) NaOH, MeOH 2: CrO3, H2SO4 / acetone 3: diethyl ether; benzene View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: CrO3, H2SO4 / acetone 2: diethyl ether; benzene View Scheme |
Epiandrosterone
A
17β-hydroxy-17α-methyl-5α-androst-2-ene
B
17β-hydroxy-17α-methyl-5α-androstan-3-ene
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane 2: 2,6-dimethylpyridine / Heating View Scheme |
3β-tosyloxy-5α-androstan-17-one
methylmagnesium bromide
A
17β-hydroxy-17α-methyl-5α-androst-2-ene
B
17β-hydroxy-17α-methyl-5α-androstan-3-ene
Conditions | Yield |
---|---|
Stage #1: 3β-tosyloxy-5α-androstan-17-one With 2,6-dimethylpyridine Heating; Stage #2: methylmagnesium bromide In tetrahydrofuran |
Conditions | Yield |
---|---|
With 3-chloro-benzenecarboperoxoic acid In chloroform for 5h; Ambient temperature; | 95% |
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; for 3h; Inert atmosphere; | 91% |
Conditions | Yield |
---|---|
(i) B2H6, THF, (ii) aq. H2O2, NaOH; Multistep reaction; | |
(i) B2H6, (ii) aq. H2O2, OH-; Multistep reaction; |
17β-hydroxy-17α-methyl-5α-androst-2-ene
2α,17β-Dihydroxy-17α-methyl-androstan
Conditions | Yield |
---|---|
(i) B2H6, THF, (ii) aq. H2O2, NaOH; Multistep reaction; | |
(i) B2H6, (ii) aq. H2O2, OH-; Multistep reaction; |
17β-hydroxy-17α-methyl-5α-androst-2-ene
(2R,3S,5S,8R,9S,10S,13S,14S,17S)-3,17-Dihydroxy-10,13,17-trimethyl-hexadecahydro-cyclopenta[a]phenanthrene-2-carbonitrile
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95 percent / m-chloroperoxybenzoic acid / CHCl3 / 5 h / Ambient temperature 2: 98 percent / toluene / 4 h / Ambient temperature View Scheme |
17β-hydroxy-17α-methyl-5α-androst-2-ene
C21H33(2)HO4
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 95 percent / m-chloroperoxybenzoic acid / CHCl3 / 5 h / Ambient temperature 2: 98 percent / toluene / 4 h / Ambient temperature 3: 10.6 percent / D2O, CH3OD, Ba(OH)2 / 48 h / 80 °C View Scheme |
The Desoxymethyltesterone, with the CAS registry number 3275-64-7, is also known as 17-Methyl-5-α-androst-2-en-17-β-ol. It belongs to the product categories of Intermediates & Fine Chemicals; Pharmaceuticals; Steroids. This chemical's molecular formula is C20H32O and molecular weight is 288.47. What's more, its systematic name is (5α,17β)-17-Methylandrost-2-en-17-ol. Its classification codes are: (1)Hormone; (2)Reproductive Effect. This chemical is an anabolic steroid. It was one of the first "designer steroids" to be marketed as a performance-enhancing drug to athletes and bodybuilders.
Physical properties of Desoxymethyltesterone are: (1)ACD/LogP: 6.41; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.41; (4)ACD/LogD (pH 7.4): 6.41; (5)ACD/BCF (pH 5.5): 43845.82; (6)ACD/BCF (pH 7.4): 43845.82; (7)ACD/KOC (pH 5.5): 73160.22; (8)ACD/KOC (pH 7.4): 73160.22; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 20.23 Å2; (13)Index of Refraction: 1.532; (14)Molar Refractivity: 87.582 cm3; (15)Molar Volume: 282.838 cm3; (16)Polarizability: 34.72×10-24cm3; (17)Surface Tension: 40.5 dyne/cm; (18)Density: 1.02 g/cm3; (19)Flash Point: 160.866 °C; (20)Enthalpy of Vaporization: 72.498 kJ/mol; (21)Boiling Point: 378.783 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: O[C@@]4([C@@]2([C@H]([C@@H]1CC[C@@H]3[C@]([C@H]1CC2)(C)C\C=C/C3)CC4)C)C
(2)Std. InChI: InChI=1S/C20H32O/c1-18-11-5-4-6-14(18)7-8-15-16(18)9-12-19(2)17(15)10-13-20(19,3)21/h4-5,14-17,21H,6-13H2,1-3H3/t14-,15-,16+,17+,18+,19+,20+/m1/s1
(3)Std. InChIKey: FRVHJVATKMIOPQ-PAPWGAKMSA-N