Tetrahedron Letters p. 3299 - 3302 (1985)
Update date:2022-08-05
Topics: Synthesis NMR spectroscopy Chiral Catalyst Enantioselective Isolation HPLC (high-performance liquid chromatography) Enantiomeric excess Reaction Conditions Chiral Auxiliary Degradation product Carzinophilin
Garner, Philip
Park, Jung Min
Rotello, Vicent
An efficient, enantioselective synthesis of (2S,3S) 4-amino-2,3-dihydroxy-3-methylbutyric acid (1) is described.The sequence includes the direct use of azide to selectively open a secondary epoxy alcohol formed under Payne rearrangement conditions.
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Doi:10.1021/ol702929k
(2008)Doi:10.1021/jm801421q
(2009)Doi:10.1016/j.tetlet.2007.12.018
(2008)Doi:10.1055/s-0031-1289304
(2011)Doi:10.1093/gerona/56.4.M243
(1958)Doi:10.1021/jo01117a017
(1956)
