Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents

DOI: 10.1016/j.bmcl.2016.07.025

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3855 - 3861 (2016)

Update date:2022-07-31

Topics:

Authors:

Minu, Maninder

Singh, Deepti

Mahaddalkar, Tejashree

Lopus, Manu

Winter, Philip

Ayoub, Ahmed T.

Missiaen, Kristal

Tilli, Tatiana Martins

Pasdar, Manijeh

Tuszynski, Jack

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Article abstract of DOI:10.1016/j.bmcl.2016.07.025

We have synthesized new, biologically active mono- and di-substituted 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives bearing electron withdrawing groups and electron donating groups. These derivative structures were characterized by their spectra

Full text of DOI:10.1016/j.bmcl.2016.07.025

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