Journal of Medicinal Chemistry p. 2464 - 2468 (1991)
Update date:2022-08-03
Topics:
Nickisch
Beier
Bittler
Elger
Laurent
Losert
Nishino
Schillinger
Wiechert
Several steroidal 6,6-ethylene-15,16-methylene 17-spirolactones were synthesized to find new progestogens that exhibit both progestational and antimineralocorticoidal activities. The influence of substituents in the 10- and 13-position of the steroidal framework on both properties was investigated. It was found that only compound 12, carrying methyl groups at the 10- and 13-positions, possesses high progestational and antimineralocorticoidal activity.
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Doi:10.1021/jo00362a005
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(2008)Doi:10.1039/jr9560004411
(1956)Doi:10.1016/j.tet.2008.01.034
(2008)Doi:10.1002/anie.200800066
(2008)Doi:10.1080/15257770701257236
(2007)
