Journal of Medicinal Chemistry p. 2464 - 2468 (1991)
Update date:2022-08-03
Topics:
Nickisch
Beier
Bittler
Elger
Laurent
Losert
Nishino
Schillinger
Wiechert
Several steroidal 6,6-ethylene-15,16-methylene 17-spirolactones were synthesized to find new progestogens that exhibit both progestational and antimineralocorticoidal activities. The influence of substituents in the 10- and 13-position of the steroidal framework on both properties was investigated. It was found that only compound 12, carrying methyl groups at the 10- and 13-positions, possesses high progestational and antimineralocorticoidal activity.
View MoreNanjing Habo Medical Technology Co., Ltd.
Contact:025－85769882
Address:No.108. Ganjiabian east. Qixia District .Nanjing
Shanghai Bojing Chemical Co., Ltd.
Contact:021-37122233
Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Contact:86-180510-83338
Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China
Guangzhou PI & PI Biotech Inc. Ltd.
Contact:+86-20-81716320
Address:13th Floor, Xinbao Technology Industrial Park, No. 2 Ruixiang Road, Huangpu District, Guangzhou,Guangdong,China
Contact:+86 512 6287 2180
Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
Doi:10.1021/jo00362a005
(1986)Doi:10.1021/ol8002749
(2008)Doi:10.1039/jr9560004411
(1956)Doi:10.1016/j.tet.2008.01.034
(2008)Doi:10.1002/anie.200800066
(2008)Doi:10.1080/15257770701257236
(2007)
