Journal of Medicinal Chemistry p. 1263 - 1269 (1986)
Update date:2022-07-30
Topics:
Ghazala, Maryam
Nair, M. G.
Toghiyani, Tahereh R.
Kisliuk, R. L.
Gaumont, Y.
Kalman, T. I.
N10-Propargylfolic acid (2), which is the closest pteridine analogue of the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (PDDF), was synthesized starting from diethyl
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