Journal of the Chemical Society. Perkin transactions I p. 2189 - 2194 (1987)
Update date:2022-09-26
Topics: Synthesis Improved synthesis Experimental (+)-milbemycin β3 3,4-dihydro-2H-pyran
Kocienski, Philip J.
Street, Stephen D. A.
Yeates, Clive
Campbell, Simon F.
A more efficient synthesis of the title compound (2), previously used in a total synthesis of (+)-milbemycin β3 (1), is described.The key step in the sequence involves a nucleophilic cleavage of the oxirane (4) by the organocuprate derived from
View Morewebsite:http://www.eastarchem.com/
Contact:1-800-898-2436
Address:1215 K Street, STE 1700
Contact:+86-29-88710656
Address:South Tai bai Road, High Tech Development Zone, Xi'an China
website:http://www.NEM.COM.CN
Contact:+86-393-4411771
Address:The west section of shengli Road,Puyang,Henan Province,China
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Shenzhen Hongyuan Import & Export Co., Ltd.
Contact:0755-26407171
Address:Shenzhen Hongyuan Chemical New Materials Technology Co., Ltd.
Doi:10.1016/S0040-4039(00)89288-6
(1985)Doi:10.1039/a705031c
(1998)Doi:10.1021/ja01343a017
(1932)Doi:10.1016/j.tet.2017.10.058
(2017)Doi:10.1080/00397910701860646
(2008)Doi:10.1016/j.tet.2008.02.020
(2008)
