Synthesis of enantiomerically pure functionalised amides (EPC-synthesis) from chiral β-aminated organolithium intermediates

DOI: 10.1016/S0040-4039(00)76980-2

Source and publish data:

Tetrahedron Letters p. 4831 - 4834 (1994)

Update date:2022-08-03

Topics: Enantiomerically pure Chiral Functionalised amides

Authors:

Foubelo, Francisco

Yus, Miguel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)76980-2

The successive deprotonation-lithiation of chiral chloroamides 1 with n-butyllithium and lithium naphthalenide, respectively, at -78°C leads to the corresponding chiral β-aminated organolithium intermediates 2, which by reaction with different electrophil

Full text of DOI:10.1016/S0040-4039(00)76980-2

Products guided by the article

Product name:(S)-N-(1-chloromethylpropyl)benzamide

Cas No:102054-15-9

R&D Labs maybe for 102054-15-9

Shao Xing Empire Import&Export CO.,ltd

Contact:86-575-82127757

Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Jinan Boss Chemical Industry Co., Ltd.【revoke the business license】

website:http://www.chemboss.com.cn

Contact:+86-531-58591595

Address:No2.Hualong Road, Jinan, China
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
Triumph International Development Limilted

website:http://www.jiashengchem.cn/

Contact:+86-536-7971999

Address:Yinhai Road,Shouguang

Relevant to this article

Preparation of nucleoside 5′-deoxy-5′-methylenephosphonates as building blocks for the synthesis of methylenephosphonate analogues

Doi:10.1039/a906066i
(1999)
Synthesis of highly functionalized pyrazines by ortho-lithiation reactions. Pyrazine ladder polymers

Doi:10.1021/ja991683p
(1999)
A fluorogenic reagent, 7-phenylsulfonyl-4-(2,1,3-benzoxadiazolyl) isocyanate for alcohols, with development based on the empirical method for prediction

Doi:10.1021/ac9905120
(1999)
Addition of acetonitrile anions to unsaturated systems under ultrasonically dispersed potassium system

Doi:10.1080/00304940109356599
(2001)
Development of a supply route for the synthesis of an iNOS inhibitor: Complications of the key S_N2 reaction

Doi:10.1021/op900108b
(2009)
Stereoselective syntheses of (-)-podorhizol lignan and its derivatives: Erythro and threo preferential aldol condensation of potassium enolate from γ-butyrolactone with alkoxybenzaldehyde

Doi:10.1271/bbb.63.1453
(1999)

Article Doi