Triflic Anhydride-Mediated Beckmann Rearrangement Reaction of β-Oximyl Amides: Access to 5-Iminooxazolines

Article abstract of DOI:10.1007/s12039-016-1085-1

Facile and efficient synthesis of 5-iminooxazolines from α,α-disubstituted β-oximyl amides mediated by triflic anhydride (Tf₂O) in the presence of 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU) in dichloromethane at room temperature is developed, and