Journal of Medicinal Chemistry p. 1159 - 1163 (1986)
Update date:2022-07-30
Topics: Chemical Structure Structure-activity study Inactivators α-Chymotrypsin
Boulanger, William A.
Katzenellenbogen, John A.
A series of 2-pyranones, bearing halogens or electron-withdrawing groups at the 6-position and alkyl, aryl, or aralkyl groups at positions 3, 4, and 5, were synthesized to investigate their binding to and inactivation of chymotrypsin.Both binding and inac
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