Effect of Methoxy Substitution on the Adrenergic Activity of Three Structurally Related α2-Adrenoreceptor Antagonists

DOI: 10.1021/jm00159a037

Source and publish data:

Journal of Medicinal Chemistry p. 1780 - 1783 (1986)

Update date:2022-07-30

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Authors:

Stillings, Michael R.

England, C. David

Welbourn, Anthony P.

Smith, Colin F. C.

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Article abstract of DOI:10.1021/jm00159a037

We have recently reported the synthesis and α₂-antagonist activity of the methoxy derivative 2 <2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline> and described the enhanced potency of this compound over the parent 1,4-benzodioxan, idazoxan, in

Full text of DOI:10.1021/jm00159a037

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