The Total Synthesis of (+/-)-N-Acetylneuraminic Acid (NANA): A Remarkable Hydroxylation of a (Z)-Enoate

DOI: 10.1021/jo00363a047

Source and publish data:

Journal of Organic Chemistry p. 2615 - 2617 (1986)

Update date:2022-08-03

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Authors:

Danishefsky, Samuel J.

DeNinno, Michael P.

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Article abstract of DOI:10.1021/jo00363a047

A total synthesis of the title compound was achieved.A key feature of the synthesis involved a stereospecific hydroxylation of a (Z)-carbomethoxyvinyl pyranoside.

Full text of DOI:10.1021/jo00363a047

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