The Stereoselective Synthesis of Acyclic and Exocyclic Trisubstituted Olefins via a Hydroxyl-Directed Wittig Reaction

DOI: 10.1021/jo00388a063

Source and publish data:

Journal of Organic Chemistry p. 2629 - 2631 (1987)

Update date:2022-08-05

Topics:

Authors:

Garner, Philip

Ramakanth, Sarabu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00388a063

Both acyclic and cyclic α-hydroxy ketones undergo an accelerated Wittig reaction with stabilized phosphonium ylides to give E-trisubstituted olefins in moderate to good chemical yield.

Full text of DOI:10.1021/jo00388a063

Products guided by the article

Product name:[2-Trimethylsilanyloxy-cyclohex-(E)-ylidene]-acetic acid methyl ester

Cas No:102675-78-5

R&D Labs maybe for 102675-78-5

Tianjin Hedong Red Cliff Chemical Reagent Factory

Contact:+86-022-84780548

Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Xinchang Jiu Xin Pharmaceutical Co., Ltd

website:http://www.jiuxinpharm.com

Contact:86 137 5756 8585

Address:Poyang industry Park
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
shandong lukang animal & plant drug trading co.,ltd.

Contact:15853765968

Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china

Relevant to this article

Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer

Doi:10.1021/acs.jmedchem.9b01659
(2020)
Mg²⁺-mediated self-assembly of an amphiphilic pyrene derivative with single-stranded DNA

Doi:10.1016/j.tetlet.2008.02.024
(2008)
Synthesis of trisubstituted furans from epoxypropargyl esters by sequential SmI₂-promoted reduction - Elimination and Pd(II)-catalyzed cycloisomerization

Doi:10.1021/jo0014257
(2001)
Copper-Catalyzed Anomeric O-Arylation of Carbohydrate Derivatives at Room Temperature

Doi:10.1021/acs.joc.9b01218
(2019)
4,4′-spirodichroman-2-ones as unexpected products from the condensation of resorcinols and dimethyl acetonedicarboxylate

Doi:10.1007/s10593-007-0041-x
(2007)
Ring Expansion of 4-(2,6-Dithiacyclohexyl)- and 4-Oxiranylcyclobuten-1-ones

Doi:10.1021/jo00108a045
(1995)

Article Doi