Synthesis of aziridines and acetidines from N-(ω-haloalkyl) imines

DOI: 10.1016/0040-4039(94)80039-1

Source and publish data:

Tetrahedron Letters p. 8023 - 8026 (1994)

Update date:2022-08-04

Topics: Synthesis Organic synthesis Aziridines

Authors:

De Kimpe

De Smaele

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Article abstract of DOI:10.1016/0040-4039(94)80039-1

N-(2-haloalkyl) and N-(3-haloalkyl) imines are convenient substrates for the synthesis of aziridines and azetidines via a two-step process involving nucleophile induced addition at the imino bond followed by intramolecular nucleophilic substitution.

Full text of DOI:10.1016/0040-4039(94)80039-1

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