NUCLEOPHILIC SUBSTITUTION AT A SATURATED CARBON ATOM WITH RETENTION OF CONFIGURATION: THE REACTION OF TRANS-2-HALO-3-TERT-BUTYLOXIRANES WITH PHENOLATES

DOI: 10.1016/S0040-4039(00)98728-8

Source and publish data:

Tetrahedron Letters p. 4337 - 4340 (1985)

Update date:2022-08-02

Topics:

Authors:

Gasteiger, Johann

Kaufmann, Karlheinz

Herzig, Christian

Bentley, T. William

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)98728-8

Whereas reaction of trans-2-chloro or 2-bromo-3-tert-butyloxirane with thiophenolate occurs at C-3 to give 2-phenylmercapto-3,3-dimethylbutanal, phenolates give substitution at C-2 with retention of the oxirane ring and retention of configuration with kin

Full text of DOI:10.1016/S0040-4039(00)98728-8

Products guided by the article

Product name:(2S,3S)-2-tert-Butyl-3-(3-methoxy-phenoxy)-oxirane

Cas No:102690-37-9

R&D Labs maybe for 102690-37-9

Changzhou Xuanming Chemical Co., Ltd.

Contact:86 0519 85525329

Address:China Town, Xinbei, Changzhou, Jiangsu Room 6019
Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang
Anyang Double Circle Auxiliary CO.,LTD

Contact:0086-134 6082 4403

Address:dongfeng road, anyang city, henan province,china
Zhangjiagang Jianing Import & Export Co.,Ltd.

Contact:086-512-55379012 13913607595

Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Beijing Chemdow Co., Ltd

website:http://www.chemdow.com

Contact:0086-10-82435335

Address:Room 401,Unit 3,4th Floor,Shangdijiayuan,Shangdi East Road, Haidian District,Beijing

Relevant to this article

Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ET(A)/ET(B) mixed antagonists

Doi:10.1021/jm970101g
(1997)
Efficient asymmetric synthesis of unnatural β-amino acids

Doi:10.1055/s-2001-16745
(2001)
Synthesis and structure-activity relationships of 3,5-disubstituted 4,5- dihydro-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ones at diazepam-sensitive and diazepam-insensitive benzodiazepine receptors

Doi:10.1021/jm00056a008
(1993)
A novel celecoxib analog UTX-121 inhibits HT1080 cell invasion by modulating membrane-type 1 matrix metalloproteinase

Doi:10.1016/j.bbrc.2019.10.092
(2020)
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα

Doi:10.1016/j.bmc.2008.01.051
(2008)
Bond distances are not always what they appear to be: Discovery and un-discovery of the longest Cr(v)≡N triple bond

Doi:10.1039/b717618j
(2008)

Article Doi