Journal of Antibiotics p. 1312 - 1321 (1994)
Update date:2022-08-05
Topics:
Arai
Kanda
Ashizawa
Morimoto
Gomi
Kono
Kasai
A series of mitomycin derivatives 1~3 having unique condenscd-ring structures was synthesized and evaluated for their anticellular and antitumor activity. These compounds were synthesized by the Michael addition of 1,3-dicarbonyl compounds to 6-demethyl-7
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