Opening of gem dicyano epoxides with amino hydrohalides: Application to the synthesis of structural analogs of tetramisole and biological evaluation

DOI: 10.1016/0223-5234(91)90064-T

Source and publish data:

European Journal of Medicinal Chemistry p. 313 - 321 (1991)

Update date:2022-07-30

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Authors:

Jaguelin

Robert Robert

Genetet Genetet

Gayral Gayral

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Article abstract of DOI:10.1016/0223-5234(91)90064-T

α-halogenamides are prepared in a onepot reaction by reacting gem dicyano epoxides with amino hydrohalides. This original reactivity of gem dicyano epoxides is used to prepare substituted [2,1-b]imidazothiazoles which are structural analogs of tetramisole

Full text of DOI:10.1016/0223-5234(91)90064-T

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