Opening of gem dicyano epoxides with amino hydrohalides: Application to the synthesis of structural analogs of tetramisole and biological evaluation

DOI: 10.1016/0223-5234(91)90064-T

Source and publish data:

European Journal of Medicinal Chemistry p. 313 - 321 (1991)

Update date:2022-07-30

Topics:

Authors:

Jaguelin

Robert Robert

Genetet Genetet

Gayral Gayral

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(91)90064-T

α-halogenamides are prepared in a onepot reaction by reacting gem dicyano epoxides with amino hydrohalides. This original reactivity of gem dicyano epoxides is used to prepare substituted [2,1-b]imidazothiazoles which are structural analogs of tetramisole

Full text of DOI:10.1016/0223-5234(91)90064-T

Products guided by the article

Product name:2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide

Cas No:102862-42-0

R&D Labs maybe for 102862-42-0

Jiangsu Feymer Technology Co., Ltd.

Contact:+86-512-58110132

Address:Fenghuang Town, Zhangjiagang City, Jiangsu Province, China
Greenutra Resource Inc

website:http://www.greenutra.cn

Contact:0086-411-39553357

Address:No. 7-1-1802, Huizhi Garden,Ocean Square,Dalian, 116033, China
Borun Chemical Co.,Ltd.

Contact:+86-574- 87178138; 87297407

Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China
Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China
Xi'an yuanfar international trade company

website:https://www.yuanfarchemical.com

Contact:86-029-88745613 ext 828

Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China

Relevant to this article

First total synthesis and absolute configuration of naturally occurring (-)-hyacinthacine A₇ and its (-)-1-epi-isomer

Doi:10.1016/j.tet.2008.03.009
(2008)
HETEROADAMANTANES AND THEIR DERIVATIVES. 6. SYNTHESIS AND MASS-SPECTROMETRIC INVESTIGATION OF 5-MONO- AND 5,6-DISUBSTITUTED 6-OXO-1,3-DIAZAADAMANTANES

Doi:10.1007/BF00842964
(1985)
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines

Doi:10.1016/j.bmc.2009.11.010
(2010)
Synthesis of bis-18,18′-desmethyl ritterazine N

Doi:10.1021/jo800454w
(2008)
Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents

Doi:10.1021/jm401208b
(2013)
The Use of Crown Ethers in Peptide Chemistry IV. Solid Phase Synthesis of Peptides Using Peptide Fragments Nα Protected With 18-Crown-6

Doi:10.1016/0040-4020(95)00206-N
(1995)

Article Doi