Efficient synthesis and biological evaluation of proximicins A, B and C

DOI: 10.1016/j.bmc.2012.01.043

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2019 - 2024 (2012)

Update date:2022-08-03

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Authors:

Brucoli, Federico

Natoli, Antonino

Marimuthu, Preethi

Borrello, Maria Teresa

Stapleton, Paul

Gibbons, Simon

Sch?tzlein, Andreas

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Article abstract of DOI:10.1016/j.bmc.2012.01.043

A quick and efficient synthesis and the biological evaluation of promising antitumor-antibiotics proximicins A, B and C are reported. The characteristic repetitive unit of these molecules, the methyl 4-Boc-aminofuran-2-carboxylate 15, was prepared in thre

Full text of DOI:10.1016/j.bmc.2012.01.043

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