Organic Letters p. 4131 - 4134 (2007)
Update date:2022-08-03
Topics:
Ye, Yue Qi
Koshino, Hiroyuki
Onose, Jun-Ichi
Yoshikawa, Kunie
Abe, Naoki
Takahashi, Shunya
Vialinin A, a powerful inhibitor (IC50 90 pM) of TNF-α production, was synthesized from sesamol in 11 steps with 28% overall yield. The key reactions include a double Suzuki coupling of electron-rich aryl triflate with phenylboronic acid and an
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