
Tetrahedron p. 4325 - 4332 (1986)
Update date:2022-07-30
Topics:
Jayamani, M.
Pant, Nalin
Ananthan, S.
Narayanan, K.
Pillai, C. N.
1,3-Diphenylpropan-2-one undergoes dehydration over alumina at around 400 deg C to form 1,3-diphenylallene which cyclizes to 2-phenylindene.Since the parent ketone can be obtained under the reaction conditions from phenylacetic acid, the present reaction forms a one step syntheses of 2-phenylindene from phenylacetic acid. 3- and 4-methylphenylacetic acids also give the corresponding indenes. 1,3-Diphenylpropan-1-ones also give phenylindenes, presumably by a direct cyclodehydration reaction.
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Doi:10.1016/S0960-894X(98)00105-X
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