
Tetrahedron p. 3559 - 3568 (1985)
Update date:2022-07-30
Topics: Reaction 1,3-Dipolar Cycloaddition Alkaloid synthesis
Smith, Richard
Livinghouse, Tom
A concise synthesis for the neurotoxic physostigmine alkaloid d,l-eserethole is described which relys upon an intramolecular cycloaddition reaction involving a "non-stabilized" imidate methylide and an unactivated alkene. The facility of this cyclization
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Doi:10.1007/s10593-014-1563-7
(2014)Doi:10.1002/chem.200701081
(2007)Doi:10.1080/00397910902730952
(2009)Doi:10.1002/adsc.202000795
(2020)Doi:10.1016/S0040-4020(01)91391-2
(1985)Doi:10.1039/DT9860000393
(1986)