Adenosine Deaminase Inhibitors. Syntheis and Biological Activity of Deaza Analogues of erythro-9-(2-Hydroxy-3-nonyl)adenine

DOI: 10.1021/jm00397a021

Source and publish data:

Journal of Medicinal Chemistry p. 390 - 393 (1988)

Update date:2022-08-03

Topics:

Authors:

Cristalli, Gloria

Franchetti, Palmarisa

Grifantini, Mario

Vittori, Sauro

Lupidi, Giulio

et al. et al.

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Article abstract of DOI:10.1021/jm00397a021

Two new deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA, 1), 7-deaza-EHNA (6) and 1,3-dodeaza-EHNA (11), were synthesized and evaluated for adenosine deaminase (ADA) inhibitory activity and compared with EHNA, 1-deaza-EHNA (2), and 3-deaza-E

Full text of DOI:10.1021/jm00397a021

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