FRIEDEL-CRAFTS ACYLATION OF 1-TERT-BUTYLDIMETHYLSILYLPYRROLE, A VERY SHORT AND SIMPLE ROUTE TO 3-SUBSTITUTED PYRROLES.

DOI: 10.1016/S0040-4039(01)80846-7

Source and publish data:

Tetrahedron Letters p. 5035 - 5036 (1985)

Update date:2022-08-04

Topics:

Authors:

Simchen, Gerhard

Majchrzak, Michal W.

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Article abstract of DOI:10.1016/S0040-4039(01)80846-7

1-tert-Butyldimethylsilylpyrrole undergoes Friedel-Crafts acylation almost exclusively at β-position giving after sodium fluoride supported hydrolysis the 3-pyrroloketones.

Full text of DOI:10.1016/S0040-4039(01)80846-7

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