Journal of Medicinal Chemistry p. 2217 - 2225 (1986)
Update date:2022-08-03
Topics:
Oiry, J.
Pue, J. Y.
Imbach, J. L.
Fatome, M.
Sentenac-Roumanou, H.
Lion, C.
A variety of N-(aminoalkanoyl)-S-acylcysteamine and N,N'-bis(aminoalkanoyl)cystamine salt derivatives were synthesized. Toxicity and radioprotective activity (as the dose reduction factor DRF) were determined in vivo on mice and compared to WR 2721 and S-acetylcysteamine hydrochloride. One of the most interesting compounds of this series was N-glycyl-S-acetylcysteamine trifluoroacetate (16, I 102). Structure-activity relationships are discussed.
View MoreChengdu Push Bio-technology Co., Ltd
Contact:86-28-85370565
Address:No.8 Wuke West Second Road, Wuhou
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Shanghai Dynamic Industrial Co.,Ltd.
website:http://www.shdynamic.com
Contact:86-021 3392 6680
Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
Zibo Fuxi'er Chemical Co.,Ltd （Shanxian Fuxi'er Chemical Co.,Ltd）
Contact:+86-533-2091422
Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
Jiaozuo Zhongwei Special Products Pharmaceutical Co.,Ltd.
website:http://www.zw-pvp.com
Contact:15302105619
Address:Jiaozuo,Henan,China (Mainland)
Doi:10.1080/00397910801997850
(2008)Doi:10.1002/adsc.200900091
(2009)Doi:10.1246/bcsj.82.555
(2009)Doi:10.1021/jo01103a614
(1958)Doi:10.1016/S0040-4039(00)98246-7
(1985)Doi:10.1021/ja8041542
(2008)
