Journal of Organic Chemistry p. 2895 - 2903 (1990)
Update date:2022-09-26
Topics:
Colucci
Tung
Petri
Rich
The coupling reagent N,N-bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl) has been used to synthesize the 2-7 hexapeptide fragment of cyclosporine A. The reagent proved useful in four of the five coupling steps with yields ranging from 78 to 92%. Ove
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