SYNTHESIS AND UNAMBIGOUS CHARACTERIZATION OF OPTICALLY PURE (+)-4-DEMETHOXYADRIAMYCIN HYDROCHLORIDE

DOI: 10.1246/cl.1984.2113

Source and publish data:

Chemistry Letters p. 2113 - 2116 (1984)

Update date:2022-08-03

Topics:

Authors:

Kimura, Yoshikazu

Suzuki, Michiyo

Terashima, Shiro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1984.2113

The title compound showing mp 226-229 deg C (decomp) and <α>²⁰_D +190 deg (CH3OH) was synthesized by two different synthetic routes and fully characterized by its spectral properties.These studies suggested that the compound previously claimed to be 4-demethoxyadriamycin hydrochloride, mp 186-188 deg C (decomp), might be (+)-14-formyloxy-4-demethoxydaunorubicin hydrochloride.

Full text of DOI:10.1246/cl.1984.2113

Products guided by the article

Product name:4-Nitro-benzoic acid (2S,3S,4S,6R)-6-[(1S,3S)-3-(2-formyloxy-acetyl)-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy]-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester

Cas No:104274-37-5

R&D Labs maybe for 104274-37-5

KangZhiYuan Pharmaceutical Company Limited

Contact:(Sabrina)86-20-85273232

Address:4th floor, building B, Dadi industry zone, Tangxia, Tianhe, Guangzhou, China
Henan Sinotech Import&Export Corporation

website:http://www.hasinotech.com

Contact:86-371-86181678

Address:No. 260, Dongming Road,Jinshui District
LinHai Cina Chemical Co., LTD.

Contact:0576-85580989

Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Changzhou LanXu Chemical Co.,ltd.(expird)

Contact:86-0519-86330911,13656129734,15261186386

Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,

Relevant to this article

Synthesis of (±)-fredericamycin A

Doi:10.1021/ja00282a042
(1986)
Conversion of 1,3-disubstituted arenes to chiral α,α-diaryl methylammonium chlorides using arene borylation

Doi:10.1016/j.tet.2008.04.060
(2008)
Dehydrative synthesis of chiral oxazolidinones catalyzed by alkali metal carbonates under low pressure of CO₂

Doi:10.1016/j.tetlet.2013.06.100
(2013)
SPERMIDINE- AND SPERMINE-LINKED CYCLOPHOSPHAZENES: NEW FORCED (BI-DANGLING AND SPIRO-BIDANGLING) MOLECULAR CONFIGURATIONS

Doi:10.1016/0022-2860(88)80254-0
(1988)
Michael addition of allenoates to electron-deficient olefins: Facile synthesis of 2-alkynyl-substituted glutaric acid derivatives

Doi:10.1021/ol801411b
(2008)
Zwitterionic diiron vinyliminium complexes: Alkylation, metalation and oxidative coupling at the S and Se functionalities

Doi:10.1016/j.jorganchem.2008.04.010
(2008)

Article Doi